Cargando…

SARS-CoV-2 Fears Green: The Chlorophyll Catabolite Pheophorbide A Is a Potent Antiviral

SARS-CoV-2 pandemic is having devastating consequences worldwide. Although vaccination advances at good pace, effectiveness against emerging variants is unpredictable. The virus has displayed a remarkable resistance to treatments and no drugs have been proved fully effective against COVID-19. Thus,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jimenez-Aleman, Guillermo H., Castro, Victoria, Londaitsbehere, Addis, Gutierrez-Rodríguez, Marta, Garaigorta, Urtzi, Solano, Roberto, Gastaminza, Pablo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538351/ https://www.ncbi.nlm.nih.gov/pubmed/34681272 http://dx.doi.org/10.3390/ph14101048

Ejemplares similares

The Chlorophyll Catabolite, Pheophorbide a, Confers Predation Resistance in a Larval Tortoise Beetle Shield Defense
por: Vencl, Fredric V., et al.
Publicado: (2009)

Chlorophyll catabolites in conditioned media of green microalga Desmodesmus subspicatus
por: Grabski, Krzysztof, et al.
Publicado: (2015)

How the Colourless ‘Nonfluorescent’ Chlorophyll Catabolites Rust
por: Ulrich, Markus, et al.
Publicado: (2011)

Structure and inhibition of SARS-CoV-1 and SARS-CoV-2 main proteases by oral antiviral compound AG7404
por: Fàbrega-Ferrer, Montserrat, et al.
Publicado: (2022)

Structure elucidation of chlorophyll catabolites (phyllobilins) by ESI-mass spectrometry—Pseudo-molecular ions and fragmentation analysis of a nonfluorescent chlorophyll catabolite (NCC)()
por: Müller, Thomas, et al.
Publicado: (2014)

Host-Directed FDA-Approved Drugs with Antiviral Activity against SARS-CoV-2 Identified by Hierarchical In Silico/In Vitro Screening Methods
por: Ginex, Tiziana, et al.
Publicado: (2021)

Chlorophyll Catabolites in Senescent Leaves of the Lime Tree (Tilia cordata)
por: Scherl, Mathias, et al.
Publicado: (2012)

Chlorophyll Catabolites in Senescent Leaves of the Plum Tree (Prunus domestica)
por: Erhart, Theresia, et al.
Publicado: (2016)

Pyro‐Phyllobilins: Elusive Chlorophyll Catabolites Lacking a Critical Carboxylate Function of the Natural Chlorophylls
por: Li, Chengjie, et al.
Publicado: (2018)

Interferon-β Stimulation Elicited by the Influenza Virus Is Regulated by the Histone Methylase Dot1L through the RIG-I-TRIM25 Signaling Axis
por: Marcos-Villar, Laura, et al.
Publicado: (2020)

Pheophorbide a: State of the Art
por: Saide, Assunta, et al.
Publicado: (2020)

Chlorophyll Catabolites – Chemical and Structural Footprints of a Fascinating Biological Phenomenon
por: Moser, Simone, et al.
Publicado: (2009)

Colorless Chlorophyll Catabolites in Senescent Florets of Broccoli (Brassica oleracea var. italica)
por: Roiser, Matthias H., et al.
Publicado: (2015)

Structures of Chlorophyll Catabolites in Bananas (Musa acuminata) Reveal a Split Path of Chlorophyll Breakdown in a Ripening Fruit
por: Moser, Simone, et al.
Publicado: (2012)

Mutation analysis of a recombinant NS replicon shows that influenza virus NS1 protein blocks the splicing and nucleo-cytoplasmic transport of its own viral mRNA
por: Garaigorta, Urtzi, et al.
Publicado: (2007)

Antiviral Activities of Ethyl Pheophorbides a and b Isolated from Aster pseudoglehnii against Influenza Viruses
por: Park, Subin, et al.
Publicado: (2022)

A Dioxobilin-Type Fluorescent Chlorophyll Catabolite as a Transient Early Intermediate of the Dioxobilin-Branch of Chlorophyll Breakdown in Arabidopsis thaliana
por: Süssenbacher, Iris, et al.
Publicado: (2015)

Hepatitis B Virus and DNA Damage Response: Interactions and Consequences for the Infection
por: Gómez-Moreno, Andoni, et al.
Publicado: (2017)

Chlorophyll Catabolites in Fall Leaves of the Wych Elm Tree Present a Novel Glycosylation Motif
por: Scherl, Mathias, et al.
Publicado: (2016)

Antiviral drugs targeting endosomal membrane proteins inhibit distant animal and human pathogenic viruses
por: Galindo, I., et al.
Publicado: (2021)

Characterization of a novel allele encoding pheophorbide a oxygenase in rice
por: Zhang, Zhihong, et al.
Publicado: (2020)

Phototherapeutic effect of transformable peptides containing pheophorbide a on colorectal cancer
por: Zhang, Zhiqin, et al.
Publicado: (2022)

Systematic HPLC/ESI-High Resolution-qTOF-MS Methodology for Metabolomic Studies in Nonfluorescent Chlorophyll Catabolites Pathway
por: Ríos, José Julián, et al.
Publicado: (2015)

Pheophorbide b ethyl ester from a chlorella vulgaris dietary supplement
por: Chee, Chin Fei, et al.
Publicado: (2008)

Photomediated Larvicidal Activity of Pheophorbide a against Cercaria Larvae of Fasciola gigantica
por: Singh, Divya Jyoti, et al.
Publicado: (2017)

Pheophorbide A and Paclitaxel Bioresponsive Nanoparticles as Double-Punch Platform for Cancer Therapy
por: Moret, Francesca, et al.
Publicado: (2021)

Zinc-Substituted Pheophorbide A Is a Safe and Efficient Antivascular Photodynamic Agent
por: Szafraniec, Milena J., et al.
Publicado: (2022)

Intratumoral Photodynamic Therapy With Newly Synthesized Pheophorbide a in Murine Oral Cancer
por: Ahn, Mee-Young, et al.
Publicado: (2017)

Triterpenes and Pheophorbides from Camellia ptilosperma and Their Cytotoxicity, Photocytotoxicity, and Photodynamic Antibacterial Activity
por: Ma, Siyuan, et al.
Publicado: (2023)

Stereo- and Regioselective Phyllobilane Oxidation in Leaf Homogenates of the Peace Lily (Spathiphyllum wallisii): Hypothetical Endogenous Path to Yellow Chlorophyll Catabolites
por: Vergeiner, Clemens, et al.
Publicado: (2015)

COVID-19 Vaccine Candidates Based on Modified Vaccinia Virus Ankara Expressing the SARS-CoV-2 Spike Protein Induce Robust T- and B-Cell Immune Responses and Full Efficacy in Mice
por: García-Arriaza, Juan, et al.
Publicado: (2021)

Photodynamic Synergistic Effect of Pheophorbide a and Doxorubicin in Combined Treatment against Tumoral Cells
por: Ruiz-González, Rubén, et al.
Publicado: (2017)

THE CHLOROPHYLL-PROTEIN COMPOUND OF THE GREEN LEAF
por: Smith, Emil L.
Publicado: (1941)

The Sensitivity of Cancer Cells to Pheophorbide a-Based Photodynamic Therapy Is Enhanced by NRF2 Silencing
por: Choi, Bo-hyun, et al.
Publicado: (2014)

Pheophorbide a Derivatives Exert Antiwrinkle Effects on UVB-Induced Skin Aging in Human Fibroblasts
por: Lee, Hwa, et al.
Publicado: (2021)

Identification of Niemann-Pick C1 protein as a potential novel SARS-CoV-2 intracellular target
por: García-Dorival, Isabel, et al.
Publicado: (2021)

Fluorescence Characteristics and Lifetime Images of Photosensitizers of Talaporfin Sodium and Sodium Pheophorbide a in Normal and Cancer Cells
por: Awasthi, Kamlesh, et al.
Publicado: (2015)

Oxidative Damage Induced by Phototoxic Pheophorbide a 17-Diethylene Glycol Ester Encapsulated in PLGA Nanoparticles
por: Mollaeva, Mariia R., et al.
Publicado: (2021)

Nanobodies Protecting From Lethal SARS-CoV-2 Infection Target Receptor Binding Epitopes Preserved in Virus Variants Other Than Omicron
por: Casasnovas, José M., et al.
Publicado: (2022)

Carbon catabolite repression in Thermoanaerobacterium saccharolyticum
por: Tsakraklides, Vasiliki, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_louha1g00lsqs9ug5a9s7kgjcb