Cargando…
Systematic Review: Microfluidics and Plasmodium
Malaria affects 228 million people worldwide each year, causing severe disease and worsening the conditions of already vulnerable populations. In this review, we explore how malaria has been detected in the past and how it can be detected in the future. Our primary focus is on finding new directions...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538353/ https://www.ncbi.nlm.nih.gov/pubmed/34683295 http://dx.doi.org/10.3390/mi12101245 |
_version_ | 1784588485815959552 |
---|---|
author | Thorne, Nicolas Flores-Olazo, Luis Egoávil-Espejo, Rocío Vela, Emir A. Noel, Julien Valdivia-Silva, Julio van Noort, Danny |
author_facet | Thorne, Nicolas Flores-Olazo, Luis Egoávil-Espejo, Rocío Vela, Emir A. Noel, Julien Valdivia-Silva, Julio van Noort, Danny |
author_sort | Thorne, Nicolas |
collection | PubMed |
description | Malaria affects 228 million people worldwide each year, causing severe disease and worsening the conditions of already vulnerable populations. In this review, we explore how malaria has been detected in the past and how it can be detected in the future. Our primary focus is on finding new directions for low-cost diagnostic methods that unspecialized personnel can apply in situ. Through this review, we show that microfluidic devices can help pre-concentrate samples of blood infected with malaria to facilitate the diagnosis. Importantly, these devices can be made cheaply and be readily deployed in remote locations. |
format | Online Article Text |
id | pubmed-8538353 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-85383532021-10-24 Systematic Review: Microfluidics and Plasmodium Thorne, Nicolas Flores-Olazo, Luis Egoávil-Espejo, Rocío Vela, Emir A. Noel, Julien Valdivia-Silva, Julio van Noort, Danny Micromachines (Basel) Review Malaria affects 228 million people worldwide each year, causing severe disease and worsening the conditions of already vulnerable populations. In this review, we explore how malaria has been detected in the past and how it can be detected in the future. Our primary focus is on finding new directions for low-cost diagnostic methods that unspecialized personnel can apply in situ. Through this review, we show that microfluidic devices can help pre-concentrate samples of blood infected with malaria to facilitate the diagnosis. Importantly, these devices can be made cheaply and be readily deployed in remote locations. MDPI 2021-10-14 /pmc/articles/PMC8538353/ /pubmed/34683295 http://dx.doi.org/10.3390/mi12101245 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Thorne, Nicolas Flores-Olazo, Luis Egoávil-Espejo, Rocío Vela, Emir A. Noel, Julien Valdivia-Silva, Julio van Noort, Danny Systematic Review: Microfluidics and Plasmodium |
title | Systematic Review: Microfluidics and Plasmodium |
title_full | Systematic Review: Microfluidics and Plasmodium |
title_fullStr | Systematic Review: Microfluidics and Plasmodium |
title_full_unstemmed | Systematic Review: Microfluidics and Plasmodium |
title_short | Systematic Review: Microfluidics and Plasmodium |
title_sort | systematic review: microfluidics and plasmodium |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538353/ https://www.ncbi.nlm.nih.gov/pubmed/34683295 http://dx.doi.org/10.3390/mi12101245 |
work_keys_str_mv | AT thornenicolas systematicreviewmicrofluidicsandplasmodium AT floresolazoluis systematicreviewmicrofluidicsandplasmodium AT egoavilespejorocio systematicreviewmicrofluidicsandplasmodium AT velaemira systematicreviewmicrofluidicsandplasmodium AT noeljulien systematicreviewmicrofluidicsandplasmodium AT valdiviasilvajulio systematicreviewmicrofluidicsandplasmodium AT vannoortdanny systematicreviewmicrofluidicsandplasmodium |