Cargando…

Systematic Review: Microfluidics and Plasmodium

Malaria affects 228 million people worldwide each year, causing severe disease and worsening the conditions of already vulnerable populations. In this review, we explore how malaria has been detected in the past and how it can be detected in the future. Our primary focus is on finding new directions...

Descripción completa

Detalles Bibliográficos
Autores principales: Thorne, Nicolas, Flores-Olazo, Luis, Egoávil-Espejo, Rocío, Vela, Emir A., Noel, Julien, Valdivia-Silva, Julio, van Noort, Danny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538353/
https://www.ncbi.nlm.nih.gov/pubmed/34683295
http://dx.doi.org/10.3390/mi12101245
_version_ 1784588485815959552
author Thorne, Nicolas
Flores-Olazo, Luis
Egoávil-Espejo, Rocío
Vela, Emir A.
Noel, Julien
Valdivia-Silva, Julio
van Noort, Danny
author_facet Thorne, Nicolas
Flores-Olazo, Luis
Egoávil-Espejo, Rocío
Vela, Emir A.
Noel, Julien
Valdivia-Silva, Julio
van Noort, Danny
author_sort Thorne, Nicolas
collection PubMed
description Malaria affects 228 million people worldwide each year, causing severe disease and worsening the conditions of already vulnerable populations. In this review, we explore how malaria has been detected in the past and how it can be detected in the future. Our primary focus is on finding new directions for low-cost diagnostic methods that unspecialized personnel can apply in situ. Through this review, we show that microfluidic devices can help pre-concentrate samples of blood infected with malaria to facilitate the diagnosis. Importantly, these devices can be made cheaply and be readily deployed in remote locations.
format Online
Article
Text
id pubmed-8538353
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-85383532021-10-24 Systematic Review: Microfluidics and Plasmodium Thorne, Nicolas Flores-Olazo, Luis Egoávil-Espejo, Rocío Vela, Emir A. Noel, Julien Valdivia-Silva, Julio van Noort, Danny Micromachines (Basel) Review Malaria affects 228 million people worldwide each year, causing severe disease and worsening the conditions of already vulnerable populations. In this review, we explore how malaria has been detected in the past and how it can be detected in the future. Our primary focus is on finding new directions for low-cost diagnostic methods that unspecialized personnel can apply in situ. Through this review, we show that microfluidic devices can help pre-concentrate samples of blood infected with malaria to facilitate the diagnosis. Importantly, these devices can be made cheaply and be readily deployed in remote locations. MDPI 2021-10-14 /pmc/articles/PMC8538353/ /pubmed/34683295 http://dx.doi.org/10.3390/mi12101245 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Thorne, Nicolas
Flores-Olazo, Luis
Egoávil-Espejo, Rocío
Vela, Emir A.
Noel, Julien
Valdivia-Silva, Julio
van Noort, Danny
Systematic Review: Microfluidics and Plasmodium
title Systematic Review: Microfluidics and Plasmodium
title_full Systematic Review: Microfluidics and Plasmodium
title_fullStr Systematic Review: Microfluidics and Plasmodium
title_full_unstemmed Systematic Review: Microfluidics and Plasmodium
title_short Systematic Review: Microfluidics and Plasmodium
title_sort systematic review: microfluidics and plasmodium
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538353/
https://www.ncbi.nlm.nih.gov/pubmed/34683295
http://dx.doi.org/10.3390/mi12101245
work_keys_str_mv AT thornenicolas systematicreviewmicrofluidicsandplasmodium
AT floresolazoluis systematicreviewmicrofluidicsandplasmodium
AT egoavilespejorocio systematicreviewmicrofluidicsandplasmodium
AT velaemira systematicreviewmicrofluidicsandplasmodium
AT noeljulien systematicreviewmicrofluidicsandplasmodium
AT valdiviasilvajulio systematicreviewmicrofluidicsandplasmodium
AT vannoortdanny systematicreviewmicrofluidicsandplasmodium