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Human Skin Permeation Enhancement Using PLGA Nanoparticles Is Mediated by Local pH Changes

The steady improvement and optimization of transdermal permeation is a constant and challenging pharmaceutical task. In this study the influence of poly(lactide-co-glycolide) (PLGA) nanoparticles on the dermal permeation of the anti-inflammatory drug flufenamic acid (FFA) was investigated. For this...

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Detalles Bibliográficos
Autores principales: Luengo, Javiana, Schneider, Marc, Schneider, Anna M., Lehr, Claus-Michael, Schaefer, Ulrich F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538358/
https://www.ncbi.nlm.nih.gov/pubmed/34683901
http://dx.doi.org/10.3390/pharmaceutics13101608

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