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Fragility Fractures: Risk Factors and Management in the Elderly

Given the progressive ageing of Western populations, the fragility fractures market has a growing socioeconomic impact. Fragility fractures are common in the elderly, negatively impacting their quality of life, limiting autonomy, increasing disability, and decreasing life expectancy. Different cause...

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Autores principales: Migliorini, Filippo, Giorgino, Riccardo, Hildebrand, Frank, Spiezia, Filippo, Peretti, Giuseppe Maria, Alessandri-Bonetti, Mario, Eschweiler, Jörg, Maffulli, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538459/
https://www.ncbi.nlm.nih.gov/pubmed/34684156
http://dx.doi.org/10.3390/medicina57101119
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author Migliorini, Filippo
Giorgino, Riccardo
Hildebrand, Frank
Spiezia, Filippo
Peretti, Giuseppe Maria
Alessandri-Bonetti, Mario
Eschweiler, Jörg
Maffulli, Nicola
author_facet Migliorini, Filippo
Giorgino, Riccardo
Hildebrand, Frank
Spiezia, Filippo
Peretti, Giuseppe Maria
Alessandri-Bonetti, Mario
Eschweiler, Jörg
Maffulli, Nicola
author_sort Migliorini, Filippo
collection PubMed
description Given the progressive ageing of Western populations, the fragility fractures market has a growing socioeconomic impact. Fragility fractures are common in the elderly, negatively impacting their quality of life, limiting autonomy, increasing disability, and decreasing life expectancy. Different causes contribute to the development of a fractures in frail individuals. Among all, targeting fragile patients before the development of a fracture may represent the greatest challenge, and current diagnostic tools suffer from limitations. This study summarizes the current evidence on the management of fragility fractures, discussing risk factors, prevention, diagnosis, and actual limitations of the clinical therapeutic options, putting forward new ideas for further scientific investigation.
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spelling pubmed-85384592021-10-24 Fragility Fractures: Risk Factors and Management in the Elderly Migliorini, Filippo Giorgino, Riccardo Hildebrand, Frank Spiezia, Filippo Peretti, Giuseppe Maria Alessandri-Bonetti, Mario Eschweiler, Jörg Maffulli, Nicola Medicina (Kaunas) Review Given the progressive ageing of Western populations, the fragility fractures market has a growing socioeconomic impact. Fragility fractures are common in the elderly, negatively impacting their quality of life, limiting autonomy, increasing disability, and decreasing life expectancy. Different causes contribute to the development of a fractures in frail individuals. Among all, targeting fragile patients before the development of a fracture may represent the greatest challenge, and current diagnostic tools suffer from limitations. This study summarizes the current evidence on the management of fragility fractures, discussing risk factors, prevention, diagnosis, and actual limitations of the clinical therapeutic options, putting forward new ideas for further scientific investigation. MDPI 2021-10-17 /pmc/articles/PMC8538459/ /pubmed/34684156 http://dx.doi.org/10.3390/medicina57101119 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Migliorini, Filippo
Giorgino, Riccardo
Hildebrand, Frank
Spiezia, Filippo
Peretti, Giuseppe Maria
Alessandri-Bonetti, Mario
Eschweiler, Jörg
Maffulli, Nicola
Fragility Fractures: Risk Factors and Management in the Elderly
title Fragility Fractures: Risk Factors and Management in the Elderly
title_full Fragility Fractures: Risk Factors and Management in the Elderly
title_fullStr Fragility Fractures: Risk Factors and Management in the Elderly
title_full_unstemmed Fragility Fractures: Risk Factors and Management in the Elderly
title_short Fragility Fractures: Risk Factors and Management in the Elderly
title_sort fragility fractures: risk factors and management in the elderly
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538459/
https://www.ncbi.nlm.nih.gov/pubmed/34684156
http://dx.doi.org/10.3390/medicina57101119
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