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Inhibition of Matrix Metalloproteinases and Cancer Cell Detachment by Ru(II) Polypyridyl Complexes Containing 4,7-Diphenyl-1,10-phenanthroline Ligands—New Candidates for Antimetastatic Agents

Primary tumor targeting is the dominant approach in drug development, while metastasis is the leading cause of cancer death. Therefore, in addition to the cytotoxic activity of a series of Ru(II) polypyridyl complexes of the type [Ru(dip)(2)L](2+) (dip: 4,7-diphenyl-1,10-phenanthroline while L = dip...

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Detalles Bibliográficos
Autores principales:	Gajda-Morszewski, Przemysław, Gurgul, Ilona, Janczy-Cempa, Ewelina, Mazuryk, Olga, Łomzik, Michał, Brindell, Małgorzata
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538513/ https://www.ncbi.nlm.nih.gov/pubmed/34681238 http://dx.doi.org/10.3390/ph14101014

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