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The Spicy Story of Cannabimimetic Indoles
The Sterling Research Group identified pravadoline as an aminoalkylindole (AAI) non-steroidal anti-inflammatory pain reliever. As drug design progressed, the ability of AAI analogs to block prostaglandin synthesis diminished, and antinociceptive activity was found to result from action at the CB(1)...
Autores principales: | Howlett, Allyn C., Thomas, Brian F., Huffman, John W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538531/ https://www.ncbi.nlm.nih.gov/pubmed/34684770 http://dx.doi.org/10.3390/molecules26206190 |
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