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Nutraceuticals for Peripheral Vestibular Pathology: Properties, Usefulness, Future Perspectives and Medico-Legal Aspects

Vestibular disorders may generate complex signs and symptoms, which may alter patients’ balance and the quality of life. Dizziness and vertigo can strongly affect daily activities and relations. Despite the presence of conventional drugs, maneuvers, and surgery, another interesting therapeutic oppor...

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Autores principales: Chiarella, Giuseppe, Marcianò, Gianmarco, Viola, Pasquale, Palleria, Caterina, Pisani, Davide, Rania, Vincenzo, Casarella, Alessandro, Astorina, Alessia, Scarpa, Alfonso, Esposito, Massimiliano, Salerno, Monica, Di Nunno, Nunzio, Bolcato, Matteo, Piscopo, Amalia, Cione, Erika, De Sarro, Giovambattista, Di Mizio, Giulio, Gallelli, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538675/
https://www.ncbi.nlm.nih.gov/pubmed/34684646
http://dx.doi.org/10.3390/nu13103646
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author Chiarella, Giuseppe
Marcianò, Gianmarco
Viola, Pasquale
Palleria, Caterina
Pisani, Davide
Rania, Vincenzo
Casarella, Alessandro
Astorina, Alessia
Scarpa, Alfonso
Esposito, Massimiliano
Salerno, Monica
Di Nunno, Nunzio
Bolcato, Matteo
Piscopo, Amalia
Cione, Erika
De Sarro, Giovambattista
Di Mizio, Giulio
Gallelli, Luca
author_facet Chiarella, Giuseppe
Marcianò, Gianmarco
Viola, Pasquale
Palleria, Caterina
Pisani, Davide
Rania, Vincenzo
Casarella, Alessandro
Astorina, Alessia
Scarpa, Alfonso
Esposito, Massimiliano
Salerno, Monica
Di Nunno, Nunzio
Bolcato, Matteo
Piscopo, Amalia
Cione, Erika
De Sarro, Giovambattista
Di Mizio, Giulio
Gallelli, Luca
author_sort Chiarella, Giuseppe
collection PubMed
description Vestibular disorders may generate complex signs and symptoms, which may alter patients’ balance and the quality of life. Dizziness and vertigo can strongly affect daily activities and relations. Despite the presence of conventional drugs, maneuvers, and surgery, another interesting therapeutic opportunity is offered by nutraceuticals. These molecules are often used in the treatment of dizziness and vertigo, but the rationale of their application is not always solidly demonstrated by the scientific evidence. Several substances have shown a variable level of efficacy/usefulness in this field, but there is lack of important evidence for most of them. From a medico-legal point of view, specific information must be provided to the patient regarding the efficacy and possibilities that the use of these preparations can allow. Administering the right nutraceutical to the proper patient is a fundamental clinical skill. Integrating conventional drug treatment with nutraceutical administration seems to be easy, but it may be difficult considering the (in part unexplored) pharmacodynamics and pharmacokinetics of nutraceuticals. The aim of the scientific community should be to elevate nutraceuticals to the same law and technical dignity of conventional drugs.
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spelling pubmed-85386752021-10-24 Nutraceuticals for Peripheral Vestibular Pathology: Properties, Usefulness, Future Perspectives and Medico-Legal Aspects Chiarella, Giuseppe Marcianò, Gianmarco Viola, Pasquale Palleria, Caterina Pisani, Davide Rania, Vincenzo Casarella, Alessandro Astorina, Alessia Scarpa, Alfonso Esposito, Massimiliano Salerno, Monica Di Nunno, Nunzio Bolcato, Matteo Piscopo, Amalia Cione, Erika De Sarro, Giovambattista Di Mizio, Giulio Gallelli, Luca Nutrients Review Vestibular disorders may generate complex signs and symptoms, which may alter patients’ balance and the quality of life. Dizziness and vertigo can strongly affect daily activities and relations. Despite the presence of conventional drugs, maneuvers, and surgery, another interesting therapeutic opportunity is offered by nutraceuticals. These molecules are often used in the treatment of dizziness and vertigo, but the rationale of their application is not always solidly demonstrated by the scientific evidence. Several substances have shown a variable level of efficacy/usefulness in this field, but there is lack of important evidence for most of them. From a medico-legal point of view, specific information must be provided to the patient regarding the efficacy and possibilities that the use of these preparations can allow. Administering the right nutraceutical to the proper patient is a fundamental clinical skill. Integrating conventional drug treatment with nutraceutical administration seems to be easy, but it may be difficult considering the (in part unexplored) pharmacodynamics and pharmacokinetics of nutraceuticals. The aim of the scientific community should be to elevate nutraceuticals to the same law and technical dignity of conventional drugs. MDPI 2021-10-18 /pmc/articles/PMC8538675/ /pubmed/34684646 http://dx.doi.org/10.3390/nu13103646 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Chiarella, Giuseppe
Marcianò, Gianmarco
Viola, Pasquale
Palleria, Caterina
Pisani, Davide
Rania, Vincenzo
Casarella, Alessandro
Astorina, Alessia
Scarpa, Alfonso
Esposito, Massimiliano
Salerno, Monica
Di Nunno, Nunzio
Bolcato, Matteo
Piscopo, Amalia
Cione, Erika
De Sarro, Giovambattista
Di Mizio, Giulio
Gallelli, Luca
Nutraceuticals for Peripheral Vestibular Pathology: Properties, Usefulness, Future Perspectives and Medico-Legal Aspects
title Nutraceuticals for Peripheral Vestibular Pathology: Properties, Usefulness, Future Perspectives and Medico-Legal Aspects
title_full Nutraceuticals for Peripheral Vestibular Pathology: Properties, Usefulness, Future Perspectives and Medico-Legal Aspects
title_fullStr Nutraceuticals for Peripheral Vestibular Pathology: Properties, Usefulness, Future Perspectives and Medico-Legal Aspects
title_full_unstemmed Nutraceuticals for Peripheral Vestibular Pathology: Properties, Usefulness, Future Perspectives and Medico-Legal Aspects
title_short Nutraceuticals for Peripheral Vestibular Pathology: Properties, Usefulness, Future Perspectives and Medico-Legal Aspects
title_sort nutraceuticals for peripheral vestibular pathology: properties, usefulness, future perspectives and medico-legal aspects
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538675/
https://www.ncbi.nlm.nih.gov/pubmed/34684646
http://dx.doi.org/10.3390/nu13103646
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