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National Monitoring of Mosquito Populations and Molecular Analysis of Flavivirus in the Republic of Korea in 2020

The Korea Disease Control and Prevention Agency has established centers at 16 locations to screen vector populations and pathogens. The aims of this study were to determine the relative spatiotemporal distributions of mosquitoes that are flavivirus vectors, and to correlate them with instances of fl...

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Autores principales: Seo, Min-Goo, Lee, Hak Seon, Yang, Sung-Chan, Noh, Byung-Eon, Kim, Tae-Kyu, Lee, Wook-Gyo, Lee, Hee Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538701/
https://www.ncbi.nlm.nih.gov/pubmed/34683405
http://dx.doi.org/10.3390/microorganisms9102085
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author Seo, Min-Goo
Lee, Hak Seon
Yang, Sung-Chan
Noh, Byung-Eon
Kim, Tae-Kyu
Lee, Wook-Gyo
Lee, Hee Il
author_facet Seo, Min-Goo
Lee, Hak Seon
Yang, Sung-Chan
Noh, Byung-Eon
Kim, Tae-Kyu
Lee, Wook-Gyo
Lee, Hee Il
author_sort Seo, Min-Goo
collection PubMed
description The Korea Disease Control and Prevention Agency has established centers at 16 locations to screen vector populations and pathogens. The aims of this study were to determine the relative spatiotemporal distributions of mosquitoes that are flavivirus vectors, and to correlate them with instances of flaviviral disease in the Republic of Korea (ROK). We collected 67,203 mosquitoes in traps at 36 collection sites in 30 urban regions and migratory bird habitats in 2020. The trap index was 36.6, and the predominant mosquito species were the Culex pipiens complex, Armigeres subalbatus, Aedes albopictus, Aedes vexans, and Culex tritaeniorhynchus. The mosquitoes were pooled into 4953 pools to monitor flavivirus infection. We determined that the minimum infection rate of flavivirus was 0.01%. Japanese encephalitis virus (JEV) was detected in only seven pools of Culex orientalis from Sangju, and we isolated JVE from two pools. All detected JEV was found to be genotype V by phylogenetic analysis. To the best of our knowledge, this is the first study to isolate genotype V JVE from Culex orientalis in the ROK. Subsequent geographical and ecological studies on mosquitoes will help improve our understanding of the relative risk of flavivirus infection. Future studies should analyze mosquito species distribution and improve flavivirus monitoring and long-term surveillance.
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spelling pubmed-85387012021-10-24 National Monitoring of Mosquito Populations and Molecular Analysis of Flavivirus in the Republic of Korea in 2020 Seo, Min-Goo Lee, Hak Seon Yang, Sung-Chan Noh, Byung-Eon Kim, Tae-Kyu Lee, Wook-Gyo Lee, Hee Il Microorganisms Article The Korea Disease Control and Prevention Agency has established centers at 16 locations to screen vector populations and pathogens. The aims of this study were to determine the relative spatiotemporal distributions of mosquitoes that are flavivirus vectors, and to correlate them with instances of flaviviral disease in the Republic of Korea (ROK). We collected 67,203 mosquitoes in traps at 36 collection sites in 30 urban regions and migratory bird habitats in 2020. The trap index was 36.6, and the predominant mosquito species were the Culex pipiens complex, Armigeres subalbatus, Aedes albopictus, Aedes vexans, and Culex tritaeniorhynchus. The mosquitoes were pooled into 4953 pools to monitor flavivirus infection. We determined that the minimum infection rate of flavivirus was 0.01%. Japanese encephalitis virus (JEV) was detected in only seven pools of Culex orientalis from Sangju, and we isolated JVE from two pools. All detected JEV was found to be genotype V by phylogenetic analysis. To the best of our knowledge, this is the first study to isolate genotype V JVE from Culex orientalis in the ROK. Subsequent geographical and ecological studies on mosquitoes will help improve our understanding of the relative risk of flavivirus infection. Future studies should analyze mosquito species distribution and improve flavivirus monitoring and long-term surveillance. MDPI 2021-10-02 /pmc/articles/PMC8538701/ /pubmed/34683405 http://dx.doi.org/10.3390/microorganisms9102085 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Seo, Min-Goo
Lee, Hak Seon
Yang, Sung-Chan
Noh, Byung-Eon
Kim, Tae-Kyu
Lee, Wook-Gyo
Lee, Hee Il
National Monitoring of Mosquito Populations and Molecular Analysis of Flavivirus in the Republic of Korea in 2020
title National Monitoring of Mosquito Populations and Molecular Analysis of Flavivirus in the Republic of Korea in 2020
title_full National Monitoring of Mosquito Populations and Molecular Analysis of Flavivirus in the Republic of Korea in 2020
title_fullStr National Monitoring of Mosquito Populations and Molecular Analysis of Flavivirus in the Republic of Korea in 2020
title_full_unstemmed National Monitoring of Mosquito Populations and Molecular Analysis of Flavivirus in the Republic of Korea in 2020
title_short National Monitoring of Mosquito Populations and Molecular Analysis of Flavivirus in the Republic of Korea in 2020
title_sort national monitoring of mosquito populations and molecular analysis of flavivirus in the republic of korea in 2020
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538701/
https://www.ncbi.nlm.nih.gov/pubmed/34683405
http://dx.doi.org/10.3390/microorganisms9102085
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