Cargando…
Palmatine, a Bioactive Protoberberine Alkaloid Isolated from Berberis cretica, Inhibits the Growth of Human Estrogen Receptor-Positive Breast Cancer Cells and Acts Synergistically and Additively with Doxorubicin
Palmatine (PLT) is a natural isoquinoline alkaloid that belongs to the class of protoberberines and exhibits a wide spectrum of pharmacological and biological properties, including anti-cancer activity. The aim of our study was to isolate PLT from the roots of Berberis cretica and investigate its cy...
Autores principales: | Grabarska, Aneta, Wróblewska-Łuczka, Paula, Kukula-Koch, Wirginia, Łuszczki, Jarogniew J., Kalpoutzakis, Eleftherios, Adamczuk, Grzegorz, Skaltsounis, Alexios Leandros, Stepulak, Andrzej |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538708/ https://www.ncbi.nlm.nih.gov/pubmed/34684834 http://dx.doi.org/10.3390/molecules26206253 |
Ejemplares similares
-
Isoquinoline Alkaloids from Coptis chinensis Franch: Focus on Coptisine as a Potential Therapeutic Candidate against Gastric Cancer Cells
por: Nakonieczna, Sylwia, et al.
Publicado: (2022) -
Synergy, Additivity, and Antagonism between Cisplatin and Selected Coumarins in Human Melanoma Cells
por: Wróblewska-Łuczka, Paula, et al.
Publicado: (2021) -
Fraxetin Interacts Additively with Cisplatin and Mitoxantrone, Antagonistically with Docetaxel in Various Human Melanoma Cell Lines—An Isobolographic Analysis
por: Wróblewska-Łuczka, Paula, et al.
Publicado: (2022) -
Heterogeneous Cellular Response of Primary and Metastatic Human Gastric Adenocarcinoma Cell Lines to Magnoflorine and Its Additive Interaction with Docetaxel
por: Grabarska, Aneta, et al.
Publicado: (2023) -
The Influence of Palmatine Isolated from Berberis sibirica Radix on Pentylenetetrazole-Induced Seizures in Zebrafish
por: Gawel, Kinga, et al.
Publicado: (2020)