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Voriconazole Pharmacokinetics Are Not Altered in Critically Ill Patients with Acute-on-Chronic Liver Failure and Continuous Renal Replacement Therapy: An Observational Study

Infection and sepsis are a main cause of acute-on-chronic liver failure (ACLF). Besides bacteria, molds play a role. Voriconazole (VRC) is recommended but its pharmacokinetics (PK) may be altered by ACLF. Because ACLF patients often suffer from concomitant acute renal failure, we studied the PK of V...

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Detalles Bibliográficos
Autores principales:	Grensemann, Jörn, Pfaffendorf, Christoph, Wicha, Sebastian G., König, Christina, Roedl, Kevin, Jarczak, Dominik, Iwersen-Bergmann, Stefanie, Manthey, Carolin, Kluge, Stefan, Fuhrmann, Valentin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538714/ https://www.ncbi.nlm.nih.gov/pubmed/34683408 http://dx.doi.org/10.3390/microorganisms9102087

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