The Influence of OAT1 Density and Functionality on Indoxyl Sulfate Transport in the Human Proximal Tubule: An Integrated Computational and In Vitro Study

Research has shown that traditional dialysis is an insufficient long-term therapy for patients suffering from end-stage kidney disease due to the high retention of uremic toxins in the blood as a result of the absence of the active transport functionality of the proximal tubule (PT). The PT’s functi...

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Detalles Bibliográficos
Autores principales: King, Jasia, Mihaila, Silvia M., Ahmed, Sabbir, Truckenmüller, Roman, Giselbrecht, Stefan, Masereeuw, Rosalinde, Carlier, Aurélie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538816/
https://www.ncbi.nlm.nih.gov/pubmed/34678967
http://dx.doi.org/10.3390/toxins13100674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538816/
https://www.ncbi.nlm.nih.gov/pubmed/34678967
http://dx.doi.org/10.3390/toxins13100674

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