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The Amyloid Fibril-Forming β-Sheet Regions of Amyloid β and α-Synuclein Preferentially Interact with the Molecular Chaperone 14-3-3ζ

14-3-3 proteins are abundant, intramolecular proteins that play a pivotal role in cellular signal transduction by interacting with phosphorylated ligands. In addition, they are molecular chaperones that prevent protein unfolding and aggregation under cellular stress conditions in a similar manner to...

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Detalles Bibliográficos
Autores principales: Williams, Danielle M., Thorn, David C., Dobson, Christopher M., Meehan, Sarah, Jackson, Sophie E., Woodcock, Joanna M., Carver, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538830/
https://www.ncbi.nlm.nih.gov/pubmed/34684701
http://dx.doi.org/10.3390/molecules26206120