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Public Willingness and Determinants of COVID-19 Vaccination at the Initial Stage of Mass Vaccination in China

The present study assessed the willingness of the general population to receive COVID-19 vaccines and identified factors that influence vaccine hesitancy and resistance. A national online survey was conducted from 29 January 2021 to 26 April 2021 in China. Multinomial logistic regression analyses we...

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Autores principales: Zhao, Yi-Miao, Liu, Lin, Sun, Jie, Yan, Wei, Yuan, Kai, Zheng, Yong-Bo, Lu, Zheng-An, Ni, Shu-Yu, Su, Si-Zhen, Zhu, Xi-Mei, Zeng, Na, Gong, Yi-Miao, Wu, Ping, Ran, Mao-Sheng, Leng, Yue, Shi, Jie, Shi, Le, Lu, Lin, Bao, Yan-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538840/
https://www.ncbi.nlm.nih.gov/pubmed/34696281
http://dx.doi.org/10.3390/vaccines9101172
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author Zhao, Yi-Miao
Liu, Lin
Sun, Jie
Yan, Wei
Yuan, Kai
Zheng, Yong-Bo
Lu, Zheng-An
Liu, Lin
Ni, Shu-Yu
Su, Si-Zhen
Zhu, Xi-Mei
Zeng, Na
Gong, Yi-Miao
Wu, Ping
Ran, Mao-Sheng
Leng, Yue
Shi, Jie
Shi, Le
Lu, Lin
Bao, Yan-Ping
author_facet Zhao, Yi-Miao
Liu, Lin
Sun, Jie
Yan, Wei
Yuan, Kai
Zheng, Yong-Bo
Lu, Zheng-An
Liu, Lin
Ni, Shu-Yu
Su, Si-Zhen
Zhu, Xi-Mei
Zeng, Na
Gong, Yi-Miao
Wu, Ping
Ran, Mao-Sheng
Leng, Yue
Shi, Jie
Shi, Le
Lu, Lin
Bao, Yan-Ping
author_sort Zhao, Yi-Miao
collection PubMed
description The present study assessed the willingness of the general population to receive COVID-19 vaccines and identified factors that influence vaccine hesitancy and resistance. A national online survey was conducted from 29 January 2021 to 26 April 2021 in China. Multinomial logistic regression analyses were conducted to identify factors that influence vaccine hesitancy and resistance. Of the 34,041 participants surveyed, 18,810 (55.3%) were willing to get vaccinated, 13,736 (40.3%) were hesitant, and 1495 (4.4%) were resistant. Rates of vaccine acceptance increased over time, with geographical discrepancies in vaccine hesitancy and resistance between provinces in China. Vaccine safety was the greatest concern expressed by most participants (24,461 [71.9%]), and the major reason for participants’ refusing vaccination (974 [65.2%]). Government agencies (23,131 [68.0%]) and social media (20,967 [61.6%]) were the main sources of COVID-19 vaccine information. Compared with vaccination acceptance, female, young and middle-aged, high income, and perceived low-risk of infection were associated with vaccine hesitancy. Histories of allergic reactions to other vaccines and depression symptoms were related to vaccine resistance. Common factors that influenced vaccine hesitancy and resistance were residing in cities and perceiving less protection with vaccines than with other protective measures. The results indicate that the rate of vaccine resistance is relatively low, but vaccine hesitancy is common. Individuals who are female, young and middle-aged, with a high income, and residing in cities are more likely to be hesitant for vaccination and should be the target populations for vaccination campaigns. Specific vaccine messaging from the government and social media could alleviate public concerns about vaccine safety and efficacy.
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spelling pubmed-85388402021-10-24 Public Willingness and Determinants of COVID-19 Vaccination at the Initial Stage of Mass Vaccination in China Zhao, Yi-Miao Liu, Lin Sun, Jie Yan, Wei Yuan, Kai Zheng, Yong-Bo Lu, Zheng-An Liu, Lin Ni, Shu-Yu Su, Si-Zhen Zhu, Xi-Mei Zeng, Na Gong, Yi-Miao Wu, Ping Ran, Mao-Sheng Leng, Yue Shi, Jie Shi, Le Lu, Lin Bao, Yan-Ping Vaccines (Basel) Article The present study assessed the willingness of the general population to receive COVID-19 vaccines and identified factors that influence vaccine hesitancy and resistance. A national online survey was conducted from 29 January 2021 to 26 April 2021 in China. Multinomial logistic regression analyses were conducted to identify factors that influence vaccine hesitancy and resistance. Of the 34,041 participants surveyed, 18,810 (55.3%) were willing to get vaccinated, 13,736 (40.3%) were hesitant, and 1495 (4.4%) were resistant. Rates of vaccine acceptance increased over time, with geographical discrepancies in vaccine hesitancy and resistance between provinces in China. Vaccine safety was the greatest concern expressed by most participants (24,461 [71.9%]), and the major reason for participants’ refusing vaccination (974 [65.2%]). Government agencies (23,131 [68.0%]) and social media (20,967 [61.6%]) were the main sources of COVID-19 vaccine information. Compared with vaccination acceptance, female, young and middle-aged, high income, and perceived low-risk of infection were associated with vaccine hesitancy. Histories of allergic reactions to other vaccines and depression symptoms were related to vaccine resistance. Common factors that influenced vaccine hesitancy and resistance were residing in cities and perceiving less protection with vaccines than with other protective measures. The results indicate that the rate of vaccine resistance is relatively low, but vaccine hesitancy is common. Individuals who are female, young and middle-aged, with a high income, and residing in cities are more likely to be hesitant for vaccination and should be the target populations for vaccination campaigns. Specific vaccine messaging from the government and social media could alleviate public concerns about vaccine safety and efficacy. MDPI 2021-10-13 /pmc/articles/PMC8538840/ /pubmed/34696281 http://dx.doi.org/10.3390/vaccines9101172 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zhao, Yi-Miao
Liu, Lin
Sun, Jie
Yan, Wei
Yuan, Kai
Zheng, Yong-Bo
Lu, Zheng-An
Liu, Lin
Ni, Shu-Yu
Su, Si-Zhen
Zhu, Xi-Mei
Zeng, Na
Gong, Yi-Miao
Wu, Ping
Ran, Mao-Sheng
Leng, Yue
Shi, Jie
Shi, Le
Lu, Lin
Bao, Yan-Ping
Public Willingness and Determinants of COVID-19 Vaccination at the Initial Stage of Mass Vaccination in China
title Public Willingness and Determinants of COVID-19 Vaccination at the Initial Stage of Mass Vaccination in China
title_full Public Willingness and Determinants of COVID-19 Vaccination at the Initial Stage of Mass Vaccination in China
title_fullStr Public Willingness and Determinants of COVID-19 Vaccination at the Initial Stage of Mass Vaccination in China
title_full_unstemmed Public Willingness and Determinants of COVID-19 Vaccination at the Initial Stage of Mass Vaccination in China
title_short Public Willingness and Determinants of COVID-19 Vaccination at the Initial Stage of Mass Vaccination in China
title_sort public willingness and determinants of covid-19 vaccination at the initial stage of mass vaccination in china
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538840/
https://www.ncbi.nlm.nih.gov/pubmed/34696281
http://dx.doi.org/10.3390/vaccines9101172
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