Cargando…
Comparison of the Effects of Chemokine Receptors CXCR2 and CXCR3 Pharmacological Modulation in Neuropathic Pain Model—In Vivo and In Vitro Study
Recent findings have highlighted the roles of CXC chemokine family in the mechanisms of neuropathic pain. Our studies provide evidence that single/repeated intrathecal administration of CXCR2 (NVP-CXCR2-20) and CXCR3 ((±)-NBI-74330) antagonists explicitly attenuated mechanical/thermal hypersensitivi...
Autores principales: | Piotrowska, Anna, Ciapała, Katarzyna, Pawlik, Katarzyna, Kwiatkowski, Klaudia, Rojewska, Ewelina, Mika, Joanna |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538855/ https://www.ncbi.nlm.nih.gov/pubmed/34681732 http://dx.doi.org/10.3390/ijms222011074 |
Ejemplares similares
-
Dataset of (±)-NBI-74330 (CXCR3 antagonist) influence on chemokines under neuropathic pain
por: Piotrowska, Anna, et al.
Publicado: (2018) -
Pharmacological Blockade of Spinal CXCL3/CXCR2 Signaling by NVP CXCR2 20, a Selective CXCR2 Antagonist, Reduces Neuropathic Pain Following Peripheral Nerve Injury
por: Piotrowska, Anna, et al.
Publicado: (2019) -
Blockade of CC Chemokine Receptor Type 3 Diminishes Pain and Enhances Opioid Analgesic Potency in a Model of Neuropathic Pain
por: Pawlik, Katarzyna, et al.
Publicado: (2021) -
Metamizole relieves pain by influencing cytokine levels in dorsal root ganglia in a rat model of neuropathic pain
por: Zajaczkowska, Renata, et al.
Publicado: (2020) -
Pharmacological Inhibition of Indoleamine 2,3-Dioxygenase-2 and Kynurenine 3-Monooxygenase, Enzymes of the Kynurenine Pathway, Significantly Diminishes Neuropathic Pain in a Rat Model
por: Rojewska, Ewelina, et al.
Publicado: (2018)