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The Hedgehog-GLI Pathway Regulates MEK5-ERK5 Expression and Activation in Melanoma Cells

Malignant melanoma is the deadliest skin cancer, with a poor prognosis in advanced stages. We recently showed that the extracellular signal-regulated kinase 5 (ERK5), encoded by the MAPK7 gene, plays a pivotal role in melanoma by regulating cell functions necessary for tumour development, such as pr...

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Detalles Bibliográficos
Autores principales:	Tusa, Ignazia, Gagliardi, Sinforosa, Tubita, Alessandro, Pandolfi, Silvia, Menconi, Alessio, Lulli, Matteo, Dello Sbarba, Persio, Stecca, Barbara, Rovida, Elisabetta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538987/ https://www.ncbi.nlm.nih.gov/pubmed/34681917 http://dx.doi.org/10.3390/ijms222011259

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