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A Marine λ-Oligocarrageenan Inhibits Migratory and Invasive Ability of MDA-MB-231 Human Breast Cancer Cells through Actions on Heparanase Metabolism and MMP-14/MMP-2 Axis

Sugar-based molecules such as heparins or natural heparan sulfate polysaccharides have been developed and widely studied for controlling heparanase (HPSE) enzymatic activity, a key player in extracellular matrix remodelling during cancer pathogenesis. However, non-enzymatic functions of HPSE have al...

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Detalles Bibliográficos
Autores principales: Cousin, Rémi, Groult, Hugo, Manseur, Chanez, Ferru-Clément, Romain, Gani, Mario, Havret, Rachel, Toucheteau, Claire, Prunier, Grégoire, Colin, Béatrice, Morel, Franck, Piot, Jean-Marie, Lanneluc, Isabelle, Baranger, Kévin, Maugard, Thierry, Fruitier-Arnaudin, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539239/
https://www.ncbi.nlm.nih.gov/pubmed/34677445
http://dx.doi.org/10.3390/md19100546