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Seroprevalence of Bartonella henselae and Bartonella quintana Infection and Impact of Related Risk Factors in People from Eastern Slovakia

The genus Bartonella is a rapidly expanding group of ubiquitous bacteria that occur mainly in different animal species, but some can also be transmitted to humans. Three species, B. henselae, B. bacilliformis, and B. quintana, are responsible for the majority of human cases. The severity of the clin...

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Autores principales: Petríková, Katarína, Halánová, Monika, Babinská, Ingrid, Logoida, Mariia, Kaliariková, Karin, Jarčuška, Peter, Dražilová, Sylvia, Sobolová, Vladimíra, Janičko, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539311/
https://www.ncbi.nlm.nih.gov/pubmed/34684210
http://dx.doi.org/10.3390/pathogens10101261
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author Petríková, Katarína
Halánová, Monika
Babinská, Ingrid
Logoida, Mariia
Kaliariková, Karin
Jarčuška, Peter
Dražilová, Sylvia
Sobolová, Vladimíra
Janičko, Martin
author_facet Petríková, Katarína
Halánová, Monika
Babinská, Ingrid
Logoida, Mariia
Kaliariková, Karin
Jarčuška, Peter
Dražilová, Sylvia
Sobolová, Vladimíra
Janičko, Martin
author_sort Petríková, Katarína
collection PubMed
description The genus Bartonella is a rapidly expanding group of ubiquitous bacteria that occur mainly in different animal species, but some can also be transmitted to humans. Three species, B. henselae, B. bacilliformis, and B. quintana, are responsible for the majority of human cases. The severity of the clinical symptoms often depends on the immune status of the patient, but others factors such as the species of the pathogen, virulence factors, and bacterial load also can play an important role. As the information on the occurrence of bartonellosis in the human population in Slovakia is absent, the aim of our pilot study was to determine the seroprevalence against B. henselae and B. quintana in the population of people living in Eastern Slovakia, and to identify the impact of related risk factors. Of 536 people included in the study, 126 (23.5%) showed positivity for anti-B. henselae antibodies and 133 (24.8%) against B. quintana. A statistically higher prevalence was confirmed only in the case of B. quintana in women regardless of the risk group. In analyzing the risk factors, we found significant differences between B. henselae seropositive and seronegative groups only in uric acid levels and serum creatinine, both, however, clinically irrelevant. Significant, but clinically irrelevant differences were observed also in alanine aminotransferase (ALT) levels and creatinine in people seropositive to B. quintana.
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spelling pubmed-85393112021-10-24 Seroprevalence of Bartonella henselae and Bartonella quintana Infection and Impact of Related Risk Factors in People from Eastern Slovakia Petríková, Katarína Halánová, Monika Babinská, Ingrid Logoida, Mariia Kaliariková, Karin Jarčuška, Peter Dražilová, Sylvia Sobolová, Vladimíra Janičko, Martin Pathogens Article The genus Bartonella is a rapidly expanding group of ubiquitous bacteria that occur mainly in different animal species, but some can also be transmitted to humans. Three species, B. henselae, B. bacilliformis, and B. quintana, are responsible for the majority of human cases. The severity of the clinical symptoms often depends on the immune status of the patient, but others factors such as the species of the pathogen, virulence factors, and bacterial load also can play an important role. As the information on the occurrence of bartonellosis in the human population in Slovakia is absent, the aim of our pilot study was to determine the seroprevalence against B. henselae and B. quintana in the population of people living in Eastern Slovakia, and to identify the impact of related risk factors. Of 536 people included in the study, 126 (23.5%) showed positivity for anti-B. henselae antibodies and 133 (24.8%) against B. quintana. A statistically higher prevalence was confirmed only in the case of B. quintana in women regardless of the risk group. In analyzing the risk factors, we found significant differences between B. henselae seropositive and seronegative groups only in uric acid levels and serum creatinine, both, however, clinically irrelevant. Significant, but clinically irrelevant differences were observed also in alanine aminotransferase (ALT) levels and creatinine in people seropositive to B. quintana. MDPI 2021-09-29 /pmc/articles/PMC8539311/ /pubmed/34684210 http://dx.doi.org/10.3390/pathogens10101261 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Petríková, Katarína
Halánová, Monika
Babinská, Ingrid
Logoida, Mariia
Kaliariková, Karin
Jarčuška, Peter
Dražilová, Sylvia
Sobolová, Vladimíra
Janičko, Martin
Seroprevalence of Bartonella henselae and Bartonella quintana Infection and Impact of Related Risk Factors in People from Eastern Slovakia
title Seroprevalence of Bartonella henselae and Bartonella quintana Infection and Impact of Related Risk Factors in People from Eastern Slovakia
title_full Seroprevalence of Bartonella henselae and Bartonella quintana Infection and Impact of Related Risk Factors in People from Eastern Slovakia
title_fullStr Seroprevalence of Bartonella henselae and Bartonella quintana Infection and Impact of Related Risk Factors in People from Eastern Slovakia
title_full_unstemmed Seroprevalence of Bartonella henselae and Bartonella quintana Infection and Impact of Related Risk Factors in People from Eastern Slovakia
title_short Seroprevalence of Bartonella henselae and Bartonella quintana Infection and Impact of Related Risk Factors in People from Eastern Slovakia
title_sort seroprevalence of bartonella henselae and bartonella quintana infection and impact of related risk factors in people from eastern slovakia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539311/
https://www.ncbi.nlm.nih.gov/pubmed/34684210
http://dx.doi.org/10.3390/pathogens10101261
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