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Streptococcus suis Isolates—Serotypes and Susceptibility to Antimicrobials in Terms of Their Use on Selected Repopulated Czech Pig Farms

Streptococcus suis represents a primary health problem (such as meningitis, septicemia and arthritis in piglets and fatteners) in the swine industry worldwide and also an emerging zoonotic pathogen. In the Czech Republic, many pig farms repopulated their herds over the past decades to reduce morbidi...

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Autores principales: Matiašovic, Ján, Nedbalcová, Kateřina, Žižlavský, Marek, Fleischer, Petr, Pokludová, Lucie, Kellnerová, Dita, Nechvátalová, Kateřina, Šimek, Bronislav, Czanderlová, Linda, Zouharová, Monika, Bernardy, Jan, Králová, Natálie, Šlosárková, Soňa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539382/
https://www.ncbi.nlm.nih.gov/pubmed/34684263
http://dx.doi.org/10.3390/pathogens10101314
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author Matiašovic, Ján
Nedbalcová, Kateřina
Žižlavský, Marek
Fleischer, Petr
Pokludová, Lucie
Kellnerová, Dita
Nechvátalová, Kateřina
Šimek, Bronislav
Czanderlová, Linda
Zouharová, Monika
Bernardy, Jan
Králová, Natálie
Šlosárková, Soňa
author_facet Matiašovic, Ján
Nedbalcová, Kateřina
Žižlavský, Marek
Fleischer, Petr
Pokludová, Lucie
Kellnerová, Dita
Nechvátalová, Kateřina
Šimek, Bronislav
Czanderlová, Linda
Zouharová, Monika
Bernardy, Jan
Králová, Natálie
Šlosárková, Soňa
author_sort Matiašovic, Ján
collection PubMed
description Streptococcus suis represents a primary health problem (such as meningitis, septicemia and arthritis in piglets and fatteners) in the swine industry worldwide and also an emerging zoonotic pathogen. In the Czech Republic, many pig farms repopulated their herds over the past decades to reduce morbidity and minimize treatment. The study analysed serotypes, sequence types and antimicrobial susceptibility in 39 S. suis isolates obtained from organs of diseased pigs from selected 16 repopulated farms with a history of S. suis-associated diseases and routine antimicrobial treatment with tulathromycin and/or amoxicillin. The analysis revealed diversity of collected isolates with regular occurrence of more than three serotypes per farm. The serotypes identified were 1/2 and 7, each in six isolates, followed by serotype 2 and 3 found in five isolates each, other serotypes were less frequent. Seven isolates were not typable by multiplex PCR and we also found sequence type of unknown type in thirteen isolates. The majority of S. suis isolates were resistant to clindamycin (n = 31), tetracycline (n = 29) and tilmicosin and tulathromycin (n = 28). On the other hand, with the exception of two isolates that were intermediately susceptible to penicillin and ampicillin, all isolates were susceptible to all three tested subgroups of beta-lactam antibiotics.
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spelling pubmed-85393822021-10-24 Streptococcus suis Isolates—Serotypes and Susceptibility to Antimicrobials in Terms of Their Use on Selected Repopulated Czech Pig Farms Matiašovic, Ján Nedbalcová, Kateřina Žižlavský, Marek Fleischer, Petr Pokludová, Lucie Kellnerová, Dita Nechvátalová, Kateřina Šimek, Bronislav Czanderlová, Linda Zouharová, Monika Bernardy, Jan Králová, Natálie Šlosárková, Soňa Pathogens Article Streptococcus suis represents a primary health problem (such as meningitis, septicemia and arthritis in piglets and fatteners) in the swine industry worldwide and also an emerging zoonotic pathogen. In the Czech Republic, many pig farms repopulated their herds over the past decades to reduce morbidity and minimize treatment. The study analysed serotypes, sequence types and antimicrobial susceptibility in 39 S. suis isolates obtained from organs of diseased pigs from selected 16 repopulated farms with a history of S. suis-associated diseases and routine antimicrobial treatment with tulathromycin and/or amoxicillin. The analysis revealed diversity of collected isolates with regular occurrence of more than three serotypes per farm. The serotypes identified were 1/2 and 7, each in six isolates, followed by serotype 2 and 3 found in five isolates each, other serotypes were less frequent. Seven isolates were not typable by multiplex PCR and we also found sequence type of unknown type in thirteen isolates. The majority of S. suis isolates were resistant to clindamycin (n = 31), tetracycline (n = 29) and tilmicosin and tulathromycin (n = 28). On the other hand, with the exception of two isolates that were intermediately susceptible to penicillin and ampicillin, all isolates were susceptible to all three tested subgroups of beta-lactam antibiotics. MDPI 2021-10-13 /pmc/articles/PMC8539382/ /pubmed/34684263 http://dx.doi.org/10.3390/pathogens10101314 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Matiašovic, Ján
Nedbalcová, Kateřina
Žižlavský, Marek
Fleischer, Petr
Pokludová, Lucie
Kellnerová, Dita
Nechvátalová, Kateřina
Šimek, Bronislav
Czanderlová, Linda
Zouharová, Monika
Bernardy, Jan
Králová, Natálie
Šlosárková, Soňa
Streptococcus suis Isolates—Serotypes and Susceptibility to Antimicrobials in Terms of Their Use on Selected Repopulated Czech Pig Farms
title Streptococcus suis Isolates—Serotypes and Susceptibility to Antimicrobials in Terms of Their Use on Selected Repopulated Czech Pig Farms
title_full Streptococcus suis Isolates—Serotypes and Susceptibility to Antimicrobials in Terms of Their Use on Selected Repopulated Czech Pig Farms
title_fullStr Streptococcus suis Isolates—Serotypes and Susceptibility to Antimicrobials in Terms of Their Use on Selected Repopulated Czech Pig Farms
title_full_unstemmed Streptococcus suis Isolates—Serotypes and Susceptibility to Antimicrobials in Terms of Their Use on Selected Repopulated Czech Pig Farms
title_short Streptococcus suis Isolates—Serotypes and Susceptibility to Antimicrobials in Terms of Their Use on Selected Repopulated Czech Pig Farms
title_sort streptococcus suis isolates—serotypes and susceptibility to antimicrobials in terms of their use on selected repopulated czech pig farms
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539382/
https://www.ncbi.nlm.nih.gov/pubmed/34684263
http://dx.doi.org/10.3390/pathogens10101314
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