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Human Antibody Domains and Fragments Targeting Neutrophil Elastase as Candidate Therapeutics for Cancer and Inflammation-Related Diseases
Neutrophil elastase (NE) is a serine protease released during neutrophil maturation. High levels of NE are related to lung tissue damage and poor prognosis in cancer; thus, NE is a potential target for therapeutic immunotherapy for multiple lung diseases and cancers. Here, we isolate and characteriz...
Autores principales: | Chu, Xiaojie, Sun, Zehua, Baek, Du-San, Li, Wei, Mellors, John W., Shapiro, Steven D., Dimitrov, Dimiter S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539514/ https://www.ncbi.nlm.nih.gov/pubmed/34681796 http://dx.doi.org/10.3390/ijms222011136 |
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