The Role of the Gastric Hormones Ghrelin and Nesfatin-1 in Reproduction

Ghrelin and nesfatin-1 are enteroendocrine peptide hormones expressed in rat X/A-like and human P/D1cells of the gastric mucosa. Besides their effect on food intake, both peptides are also implicated in various other physiological systems. One of these is the reproductive system. This present review...

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Autores principales: Schalla, Martha A., Stengel, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539660/
https://www.ncbi.nlm.nih.gov/pubmed/34681721
http://dx.doi.org/10.3390/ijms222011059
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author Schalla, Martha A.
Stengel, Andreas
author_facet Schalla, Martha A.
Stengel, Andreas
author_sort Schalla, Martha A.
collection PubMed
description Ghrelin and nesfatin-1 are enteroendocrine peptide hormones expressed in rat X/A-like and human P/D1cells of the gastric mucosa. Besides their effect on food intake, both peptides are also implicated in various other physiological systems. One of these is the reproductive system. This present review illustrates the distribution of ghrelin and nesfatin-1 along the hypothalamus–pituitary–gonadal (HPG) axis, their modulation by reproductive hormones, and effects on reproductive functions as well as highlighting gaps in current knowledge to foster further research.
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spelling pubmed-85396602021-10-24 The Role of the Gastric Hormones Ghrelin and Nesfatin-1 in Reproduction Schalla, Martha A. Stengel, Andreas Int J Mol Sci Review Ghrelin and nesfatin-1 are enteroendocrine peptide hormones expressed in rat X/A-like and human P/D1cells of the gastric mucosa. Besides their effect on food intake, both peptides are also implicated in various other physiological systems. One of these is the reproductive system. This present review illustrates the distribution of ghrelin and nesfatin-1 along the hypothalamus–pituitary–gonadal (HPG) axis, their modulation by reproductive hormones, and effects on reproductive functions as well as highlighting gaps in current knowledge to foster further research. MDPI 2021-10-14 /pmc/articles/PMC8539660/ /pubmed/34681721 http://dx.doi.org/10.3390/ijms222011059 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Schalla, Martha A.
Stengel, Andreas
The Role of the Gastric Hormones Ghrelin and Nesfatin-1 in Reproduction
title The Role of the Gastric Hormones Ghrelin and Nesfatin-1 in Reproduction
title_full The Role of the Gastric Hormones Ghrelin and Nesfatin-1 in Reproduction
title_fullStr The Role of the Gastric Hormones Ghrelin and Nesfatin-1 in Reproduction
title_full_unstemmed The Role of the Gastric Hormones Ghrelin and Nesfatin-1 in Reproduction
title_short The Role of the Gastric Hormones Ghrelin and Nesfatin-1 in Reproduction
title_sort role of the gastric hormones ghrelin and nesfatin-1 in reproduction
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539660/
https://www.ncbi.nlm.nih.gov/pubmed/34681721
http://dx.doi.org/10.3390/ijms222011059
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