Synthesis, In Silico Prediction and In Vitro Evaluation of Antimicrobial Activity, DFT Calculation and Theoretical Investigation of Novel Xanthines and Uracil Containing Imidazolone Derivatives

Novel xanthine and imidazolone derivatives were synthesized based on oxazolone derivatives 2a-c as a key intermediate. The corresponding xanthine 3-5 and imidazolone derivatives 6-13 were obtained via reaction of oxazolone derivative 2a-c with 5,6-diaminouracils 1a-e under various conditions. Xanthi...

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Detalles Bibliográficos
Autores principales: El-Kalyoubi, Samar, Agili, Fatimah, Zordok, Wael A., El-Sayed, Ashraf S. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539769/
https://www.ncbi.nlm.nih.gov/pubmed/34681643
http://dx.doi.org/10.3390/ijms222010979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539769/
https://www.ncbi.nlm.nih.gov/pubmed/34681643
http://dx.doi.org/10.3390/ijms222010979

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