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Molecular response to PARP1 inhibition in ovarian cancer cells as determined by mass spectrometry based proteomics

BACKGROUND: Poly (ADP)-ribose polymerase (PARP) inhibitors have entered routine clinical practice for the treatment of high-grade serous ovarian cancer (HGSOC), yet the molecular mechanisms underlying treatment response to PARP1 inhibition (PARP1i) are not fully understood. METHODS: Here, we used un...

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Detalles Bibliográficos
Autores principales:	Franz, Alexandra, Coscia, Fabian, Shen, Ciyue, Charaoui, Lea, Mann, Matthias, Sander, Chris
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539835/ https://www.ncbi.nlm.nih.gov/pubmed/34686201 http://dx.doi.org/10.1186/s13048-021-00886-x

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