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Chemical Composition, Antibacterial and Antifungal Activity of the Essential Oil from Cistus ladanifer L.

Cistus ladanifer L. is a plant widely used in folk medicine to treat various illnesses. This study aims to evaluate the effect of the plant flourishing time harvest on the chemical composition and the antimicrobial effect of its essential oil. Chemical analysis of the essential oil was carried out u...

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Autores principales: El Karkouri, Jamila, Bouhrim, Mohamed, Al Kamaly, Omkulthom Mohamed, Mechchate, Hamza, Kchibale, Amal, Adadi, Imad, Amine, Sanae, Alaoui Ismaili, Souâd, Zair, Touriya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539845/
https://www.ncbi.nlm.nih.gov/pubmed/34685879
http://dx.doi.org/10.3390/plants10102068
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author El Karkouri, Jamila
Bouhrim, Mohamed
Al Kamaly, Omkulthom Mohamed
Mechchate, Hamza
Kchibale, Amal
Adadi, Imad
Amine, Sanae
Alaoui Ismaili, Souâd
Zair, Touriya
author_facet El Karkouri, Jamila
Bouhrim, Mohamed
Al Kamaly, Omkulthom Mohamed
Mechchate, Hamza
Kchibale, Amal
Adadi, Imad
Amine, Sanae
Alaoui Ismaili, Souâd
Zair, Touriya
author_sort El Karkouri, Jamila
collection PubMed
description Cistus ladanifer L. is a plant widely used in folk medicine to treat various illnesses. This study aims to evaluate the effect of the plant flourishing time harvest on the chemical composition and the antimicrobial effect of its essential oil. Chemical analysis of the essential oil was carried out using gas chromatography-mass spectrometry (GC-MS). The antibacterial and antifungal proprieties were tested against four selected bacteria (Staphylococcus aureus, Salmonella Typhi, Escherichia coli, and Acinetobacter baumannii) and nine fungi (Yeasts (Candida tropicalis, Candida glabrata, Candida dubliniensis, Candida sp., Rhodotorula rubra, Cryptococcus neoformans) and molds (Penicillium sp. (P), Fusarium sp. (F), Aspergillus niger (A. niger)), respectively. The essential oil of C. ladanifer demonstrated a powerful antibacterial activity with an inhibition zone of 55 ± 0.22 mm for Staphylococcus aureus, 42 ± 0.11 mm for Escherichia coli, 35 ± 0.27 mm for Acinetobacter baumannii (Full resistant to antibiotics) and 30 ± 0.25 mm for Salmonella Typhi. It also inhibited all tested bacteria at 10 µL/mL. For the antifungal activity test, C. tropicalis and C. neoformans appeared to be the most sensitive strains to the essential oil with an inhibition zone of 13 mm, followed by R. rubra and Penicillium sp. (12 mm), then C. dubliniensis and C. glabrata (11 mm). The chemical analysis of the essential oil by GC-MS revealed that the major components of the essential oil were viridiflorol (17.64%), pinocarveol (11.02%), bornylacetate (9.38%), and ledol (8.85%). C. ladanifer exhibited a remarkable antimicrobial activity that could be more exploited to develop targeted natural remedies against specific diseases.
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spelling pubmed-85398452021-10-24 Chemical Composition, Antibacterial and Antifungal Activity of the Essential Oil from Cistus ladanifer L. El Karkouri, Jamila Bouhrim, Mohamed Al Kamaly, Omkulthom Mohamed Mechchate, Hamza Kchibale, Amal Adadi, Imad Amine, Sanae Alaoui Ismaili, Souâd Zair, Touriya Plants (Basel) Article Cistus ladanifer L. is a plant widely used in folk medicine to treat various illnesses. This study aims to evaluate the effect of the plant flourishing time harvest on the chemical composition and the antimicrobial effect of its essential oil. Chemical analysis of the essential oil was carried out using gas chromatography-mass spectrometry (GC-MS). The antibacterial and antifungal proprieties were tested against four selected bacteria (Staphylococcus aureus, Salmonella Typhi, Escherichia coli, and Acinetobacter baumannii) and nine fungi (Yeasts (Candida tropicalis, Candida glabrata, Candida dubliniensis, Candida sp., Rhodotorula rubra, Cryptococcus neoformans) and molds (Penicillium sp. (P), Fusarium sp. (F), Aspergillus niger (A. niger)), respectively. The essential oil of C. ladanifer demonstrated a powerful antibacterial activity with an inhibition zone of 55 ± 0.22 mm for Staphylococcus aureus, 42 ± 0.11 mm for Escherichia coli, 35 ± 0.27 mm for Acinetobacter baumannii (Full resistant to antibiotics) and 30 ± 0.25 mm for Salmonella Typhi. It also inhibited all tested bacteria at 10 µL/mL. For the antifungal activity test, C. tropicalis and C. neoformans appeared to be the most sensitive strains to the essential oil with an inhibition zone of 13 mm, followed by R. rubra and Penicillium sp. (12 mm), then C. dubliniensis and C. glabrata (11 mm). The chemical analysis of the essential oil by GC-MS revealed that the major components of the essential oil were viridiflorol (17.64%), pinocarveol (11.02%), bornylacetate (9.38%), and ledol (8.85%). C. ladanifer exhibited a remarkable antimicrobial activity that could be more exploited to develop targeted natural remedies against specific diseases. MDPI 2021-09-30 /pmc/articles/PMC8539845/ /pubmed/34685879 http://dx.doi.org/10.3390/plants10102068 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
El Karkouri, Jamila
Bouhrim, Mohamed
Al Kamaly, Omkulthom Mohamed
Mechchate, Hamza
Kchibale, Amal
Adadi, Imad
Amine, Sanae
Alaoui Ismaili, Souâd
Zair, Touriya
Chemical Composition, Antibacterial and Antifungal Activity of the Essential Oil from Cistus ladanifer L.
title Chemical Composition, Antibacterial and Antifungal Activity of the Essential Oil from Cistus ladanifer L.
title_full Chemical Composition, Antibacterial and Antifungal Activity of the Essential Oil from Cistus ladanifer L.
title_fullStr Chemical Composition, Antibacterial and Antifungal Activity of the Essential Oil from Cistus ladanifer L.
title_full_unstemmed Chemical Composition, Antibacterial and Antifungal Activity of the Essential Oil from Cistus ladanifer L.
title_short Chemical Composition, Antibacterial and Antifungal Activity of the Essential Oil from Cistus ladanifer L.
title_sort chemical composition, antibacterial and antifungal activity of the essential oil from cistus ladanifer l.
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539845/
https://www.ncbi.nlm.nih.gov/pubmed/34685879
http://dx.doi.org/10.3390/plants10102068
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