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Investigation of Marine-Derived Natural Products as Raf Kinase Inhibitory Protein (RKIP)-Binding Ligands

Raf kinase inhibitory protein (RKIP) is an essential regulator of the Ras/Raf-1/MEK/ERK signaling cascade and functions by directly interacting with the Raf-1 kinase. The abnormal expression of RKIP is linked with numerous diseases including cancers, Alzheimer’s and diabetic nephropathy. Interesting...

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Detalles Bibliográficos
Autores principales:	Parate, Shraddha, Kumar, Vikas, Hong, Jong Chan, Lee, Keun Woo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539980/ https://www.ncbi.nlm.nih.gov/pubmed/34677480 http://dx.doi.org/10.3390/md19100581

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