Cargando…
Structural and functional stability of the sulfur-free surfactant protein B peptide mimic B-YL in synthetic surfactant lipids
BACKGROUND: Optimal functionality of synthetic lung surfactant for treatment of respiratory distress syndrome in preterm infants largely depends on the quality and quantity of the surfactant protein B (SP-B) peptide mimic and the lipid mixture. B-YL peptide is a 41-residue sulfur-free SP-B mimic wit...
Autores principales: | Walther, Frans J., Sharma, Shantanu, Gordon, Larry M., Waring, Alan J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540162/ https://www.ncbi.nlm.nih.gov/pubmed/34686153 http://dx.doi.org/10.1186/s12890-021-01695-0 |
Ejemplares similares
-
Design of Surfactant Protein B Peptide Mimics Based on the Saposin Fold for Synthetic Lung Surfactants
por: Walther, Frans J., et al.
Publicado: (2016) -
A sulfur-free peptide mimic of surfactant protein B (B-YL) exhibits high in vitro and in vivo surface activities
por: Walther, Frans J., et al.
Publicado: (2018) -
Emulation of the structure of the Saposin protein fold by a lung surfactant peptide construct of surfactant Protein B
por: Waring, Alan J., et al.
Publicado: (2022) -
Lung Surfactant Protein B Peptide Mimics Interact with the Human ACE2 Receptor
por: Waring, Alan J., et al.
Publicado: (2023) -
Synthetic surfactant containing SP-B and SP-C mimics is superior to single-peptide formulations in rabbits with chemical acute lung injury
por: Walther, Frans J., et al.
Publicado: (2014)