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Larotinib in patients with advanced and previously treated esophageal squamous cell carcinoma with epidermal growth factor receptor overexpression or amplification: an open-label, multicenter phase 1b study

BACKGROUND: Larotinib is a new first-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor. This open-label, phase 1b study is aimed to evaluate the efficacy, safety of larotinib in patients with advanced esophageal squamous cell carcinoma (ESCC) with EGFR overexpression or am...

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Detalles Bibliográficos
Autores principales:	Liu, Rongrui, Liu, Lianke, Zhao, Chuanhua, Bai, Yuxian, Zheng, Yulong, Zhang, Shu, Li, Ning, Yang, Jianwei, Fan, Qingxia, Wang, Xiuwen, Zeng, Shan, Zhang, Yingjun, Zhang, Weihong, Zhuang, Yulei, Kang, Ning, Jiang, Yingzhi, Sun, Hongmei, Xu, Jianming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540164/ https://www.ncbi.nlm.nih.gov/pubmed/34688250 http://dx.doi.org/10.1186/s12876-021-01982-4

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