Gag-Gag Interactions Are Insufficient to Fully Stabilize and Order the Immature HIV Gag Lattice

Immature HIV virions harbor a lattice of Gag molecules with significant ordering in CA-NTD, CA-CTD and SP1 regions. This ordering plays a major role during HIV maturation. To test the condition in which the Gag lattice forms in vivo, we assembled virus like particles (VLPs) by expressing only HIV Ga...

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Detalles Bibliográficos
Autores principales: Saha, Ipsita, Preece, Benjamin, Peterson, Abby, Durden, Haley, MacArthur, Brian, Lowe, Jake, Belnap, David, Vershinin, Michael, Saffarian, Saveez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540168/
https://www.ncbi.nlm.nih.gov/pubmed/34696376
http://dx.doi.org/10.3390/v13101946

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