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Precise Characterization of Genetic Interactions in Cancer via Molecular Network Refining Processes
Genetic interactions (GIs), such as the synthetic lethal interaction, are promising therapeutic targets in precision medicine. However, despite extensive efforts to characterize GIs by large-scale perturbation screening, considerable false positives have been reported in multiple studies. We propose...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540220/ https://www.ncbi.nlm.nih.gov/pubmed/34681774 http://dx.doi.org/10.3390/ijms222011114 |