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Physiologic Effects of Instilled and Aerosolized Surfactant Using a Breath-Synchronized Nebulizer on Surfactant-Deficient Rabbits †

Surfactant administration incorporates liquid bolus instillation via endotracheal tube catheter and use of a mechanical ventilator. Aerosolized surfactant has generated interest and conflicting data related to dose requirements and efficacy. We hypothesized that aerosolized surfactant with a novel b...

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Detalles Bibliográficos
Autores principales: DiBlasi, Robert M., Micheletti, Kellie J., Zimmerman, Joseph D., Poli, Jonathan A., Fink, James B., Kajimoto, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540270/
https://www.ncbi.nlm.nih.gov/pubmed/34683873
http://dx.doi.org/10.3390/pharmaceutics13101580