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Magnetically Assisted Drug Delivery of Topical Eye Drops Maintains Retinal Function In Vivo in Mice

Barded-Biedl syndrome (BBS) is a rare genetic disorder with an unmet medical need for retinal degeneration. Small-molecule drugs were previously identified to slow down the apoptosis of photoreceptors in BBS mouse models. Clinical translation was not practical due to the necessity of repetitive inva...

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Detalles Bibliográficos
Autores principales: Bassetto, Marco, Ajoy, Daniel, Poulhes, Florent, Obringer, Cathy, Walter, Aurelie, Messadeq, Nadia, Sadeghi, Amir, Puranen, Jooseppi, Ruponen, Marika, Kettunen, Mikko, Toropainen, Elisa, Urtti, Arto, Dollfus, Hélène, Zelphati, Olivier, Marion, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540400/
https://www.ncbi.nlm.nih.gov/pubmed/34683941
http://dx.doi.org/10.3390/pharmaceutics13101650