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Population Pharmacokinetics of Levetiracetam and Dosing Evaluation in Critically Ill Patients with Normal or Augmented Renal Function

Levetiracetam is a broad-spectrum antiepileptic drug commonly used in intensive care units (ICUs). The objective of this study is to evaluate the adequacy of levetiracetam dosing in patients with normal or augmented renal clearance (ARC) admitted to the ICU by population modelling and simulation. A...

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Detalles Bibliográficos
Autores principales: Bilbao-Meseguer, Idoia, Barrasa, Helena, Asín-Prieto, Eduardo, Alarcia-Lacalle, Ana, Rodríguez-Gascón, Alicia, Maynar, Javier, Sánchez-Izquierdo, José Ángel, Balziskueta, Goiatz, Griffith, María Sánchez-Bayton, Quilez Trasobares, Nerea, Solinís, María Ángeles, Isla, Arantxa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540413/
https://www.ncbi.nlm.nih.gov/pubmed/34683983
http://dx.doi.org/10.3390/pharmaceutics13101690

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