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Population Pharmacokinetics of Levetiracetam and Dosing Evaluation in Critically Ill Patients with Normal or Augmented Renal Function
Levetiracetam is a broad-spectrum antiepileptic drug commonly used in intensive care units (ICUs). The objective of this study is to evaluate the adequacy of levetiracetam dosing in patients with normal or augmented renal clearance (ARC) admitted to the ICU by population modelling and simulation. A...
Autores principales: | Bilbao-Meseguer, Idoia, Barrasa, Helena, Asín-Prieto, Eduardo, Alarcia-Lacalle, Ana, Rodríguez-Gascón, Alicia, Maynar, Javier, Sánchez-Izquierdo, José Ángel, Balziskueta, Goiatz, Griffith, María Sánchez-Bayton, Quilez Trasobares, Nerea, Solinís, María Ángeles, Isla, Arantxa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540413/ https://www.ncbi.nlm.nih.gov/pubmed/34683983 http://dx.doi.org/10.3390/pharmaceutics13101690 |
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