Selection and Incorporation of siRNA Carrying Non-Viral Vector for Sustained Delivery from Gellan Gum Hydrogels

The local controlled release of siRNA is an attractive and rational strategy to enhance and extend the effectiveness of gene therapy. Since naked and unmodified siRNA has a limited cell uptake and knockdown efficiency, the complexation of siRNA with non-viral carriers is often necessary for the deli...

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Detalles Bibliográficos
Autores principales: Nalbadis, Anastasios, Trutschel, Marie-Luise, Lucas, Henrike, Luetzkendorf, Jana, Meister, Annette, Mäder, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540443/
https://www.ncbi.nlm.nih.gov/pubmed/34683839
http://dx.doi.org/10.3390/pharmaceutics13101546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540443/
https://www.ncbi.nlm.nih.gov/pubmed/34683839
http://dx.doi.org/10.3390/pharmaceutics13101546

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