A Novel Real-Time RT-PCR-Based Methodology for the Preliminary Typing of SARS-CoV-2 Variants, Employing Non-Extendable LNA Oligonucleotides and Three Signature Mutations at the Spike Protein Receptor-Binding Domain

Mutations resulting in amino-acid substitutions of the SARS-CoV-2 spike protein receptor-binding domain (RBD) have been associated with enhanced transmissibility and immune escape of the respective variants, namely Alpha, Beta, Gamma or Delta. Rapid identification of the aforementioned variants of c...

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Detalles Bibliográficos
Autores principales: Chaintoutis, Serafeim C., Chassalevris, Taxiarchis, Balaska, Sofia, Mouchtaropoulou, Evangelia, Tsiolas, George, Vlatakis, Ioannis, Tychala, Areti, Koutsioulis, Dimitris, Argiriou, Anagnostis, Skoura, Lemonia, Dovas, Chrysostomos I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540511/
https://www.ncbi.nlm.nih.gov/pubmed/34685386
http://dx.doi.org/10.3390/life11101015

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