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Oxygen Toxicity to the Immature Lung—Part I: Pathomechanistic Understanding and Preclinical Perspectives

In utero, the fetus and its lungs develop in a hypoxic environment, where HIF-1α and VEGFA signaling constitute major determinants of further development. Disruption of this homeostasis after preterm delivery and extrauterine exposure to high fractions of oxygen are among the key events leading to b...

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Detalles Bibliográficos
Autores principales: Choi, Yesi, Rekers, Lisa, Dong, Ying, Holzfurtner, Lena, Goetz, Maurizio J., Shahzad, Tayyab, Zimmer, Klaus-Peter, Behnke, Judith, Behnke, Jonas, Bellusci, Saverio, Ehrhardt, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540649/
https://www.ncbi.nlm.nih.gov/pubmed/34681665
http://dx.doi.org/10.3390/ijms222011006