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Oxygen Toxicity to the Immature Lung—Part I: Pathomechanistic Understanding and Preclinical Perspectives
In utero, the fetus and its lungs develop in a hypoxic environment, where HIF-1α and VEGFA signaling constitute major determinants of further development. Disruption of this homeostasis after preterm delivery and extrauterine exposure to high fractions of oxygen are among the key events leading to b...
Autores principales: | Choi, Yesi, Rekers, Lisa, Dong, Ying, Holzfurtner, Lena, Goetz, Maurizio J., Shahzad, Tayyab, Zimmer, Klaus-Peter, Behnke, Judith, Behnke, Jonas, Bellusci, Saverio, Ehrhardt, Harald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540649/ https://www.ncbi.nlm.nih.gov/pubmed/34681665 http://dx.doi.org/10.3390/ijms222011006 |
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