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Coronary Artery Disease in Patients Older than 35 and Eligible for Cardiovascular Secondary Prevention: An Italian Retrospective Observational Analysis of Healthcare Administrative Databases

Background: This study describes patients with coronary artery disease (CAD) who are eligible for secondary prevention and assesses their healthcare consumption and costs from the perspective of the Italian National Health Service (INHS). Methods: From the Fondazione Ricerca e Salute’s database, whi...

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Autores principales: Calabria, Silvia, Ronconi, Giulia, Dondi, Letizia, Piccinni, Carlo, Cinconze, Enrico, Pedrini, Antonella, Esposito, Immacolata, Addesi, Alice, Martini, Nello, Maggioni, Aldo Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540912/
https://www.ncbi.nlm.nih.gov/pubmed/34682831
http://dx.doi.org/10.3390/jcm10204708
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author Calabria, Silvia
Ronconi, Giulia
Dondi, Letizia
Piccinni, Carlo
Cinconze, Enrico
Pedrini, Antonella
Esposito, Immacolata
Addesi, Alice
Martini, Nello
Maggioni, Aldo Pietro
author_facet Calabria, Silvia
Ronconi, Giulia
Dondi, Letizia
Piccinni, Carlo
Cinconze, Enrico
Pedrini, Antonella
Esposito, Immacolata
Addesi, Alice
Martini, Nello
Maggioni, Aldo Pietro
author_sort Calabria, Silvia
collection PubMed
description Background: This study describes patients with coronary artery disease (CAD) who are eligible for secondary prevention and assesses their healthcare consumption and costs from the perspective of the Italian National Health Service (INHS). Methods: From the Fondazione Ricerca e Salute’s database, which collects Italian healthcare administrative data, all patients aged ≥ 35, with ≥1 primary in-hospital CAD diagnosis and/or procedure on the coronary arteries, or with the specific disease exemption code, and who are suitable for long-term secondary prevention treatments, were identified in 2018 and analyzed. Demographics, comorbidities, one-year supplied drugs, hospitalizations, and costs were analyzed. Results: From >3 million inhabitants aged ≥ 35, 46,063 (1.3%) were identified (72.1% males, mean age 70 ± 12; approximately 50% with ≥3 comorbidities). During a one-year follow-up, 96.4% were treated with ≥1 drug for secondary prevention (mainly antiplatelets and lipid lowering agents), 69.4% with ≥1 concomitant cardiovascular drug, and 95.8% with ≥1 concomitant non-cardiovascular therapy. Within one year, 30.6% of patients were hospitalized at least once, mostly due to non-cardiovascular events. Calculated by mean, the INHS paid EUR 6078 per patient. Conclusions: This analysis confirms the relevant burden of CAD for patients with many comorbidities and who are frequently hospitalized, and the burden on the INHS. A multidisciplinary healthcare approach is encouraged to improve patients’ outcomes and reduce costs for the INHS.
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spelling pubmed-85409122021-10-24 Coronary Artery Disease in Patients Older than 35 and Eligible for Cardiovascular Secondary Prevention: An Italian Retrospective Observational Analysis of Healthcare Administrative Databases Calabria, Silvia Ronconi, Giulia Dondi, Letizia Piccinni, Carlo Cinconze, Enrico Pedrini, Antonella Esposito, Immacolata Addesi, Alice Martini, Nello Maggioni, Aldo Pietro J Clin Med Article Background: This study describes patients with coronary artery disease (CAD) who are eligible for secondary prevention and assesses their healthcare consumption and costs from the perspective of the Italian National Health Service (INHS). Methods: From the Fondazione Ricerca e Salute’s database, which collects Italian healthcare administrative data, all patients aged ≥ 35, with ≥1 primary in-hospital CAD diagnosis and/or procedure on the coronary arteries, or with the specific disease exemption code, and who are suitable for long-term secondary prevention treatments, were identified in 2018 and analyzed. Demographics, comorbidities, one-year supplied drugs, hospitalizations, and costs were analyzed. Results: From >3 million inhabitants aged ≥ 35, 46,063 (1.3%) were identified (72.1% males, mean age 70 ± 12; approximately 50% with ≥3 comorbidities). During a one-year follow-up, 96.4% were treated with ≥1 drug for secondary prevention (mainly antiplatelets and lipid lowering agents), 69.4% with ≥1 concomitant cardiovascular drug, and 95.8% with ≥1 concomitant non-cardiovascular therapy. Within one year, 30.6% of patients were hospitalized at least once, mostly due to non-cardiovascular events. Calculated by mean, the INHS paid EUR 6078 per patient. Conclusions: This analysis confirms the relevant burden of CAD for patients with many comorbidities and who are frequently hospitalized, and the burden on the INHS. A multidisciplinary healthcare approach is encouraged to improve patients’ outcomes and reduce costs for the INHS. MDPI 2021-10-14 /pmc/articles/PMC8540912/ /pubmed/34682831 http://dx.doi.org/10.3390/jcm10204708 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Calabria, Silvia
Ronconi, Giulia
Dondi, Letizia
Piccinni, Carlo
Cinconze, Enrico
Pedrini, Antonella
Esposito, Immacolata
Addesi, Alice
Martini, Nello
Maggioni, Aldo Pietro
Coronary Artery Disease in Patients Older than 35 and Eligible for Cardiovascular Secondary Prevention: An Italian Retrospective Observational Analysis of Healthcare Administrative Databases
title Coronary Artery Disease in Patients Older than 35 and Eligible for Cardiovascular Secondary Prevention: An Italian Retrospective Observational Analysis of Healthcare Administrative Databases
title_full Coronary Artery Disease in Patients Older than 35 and Eligible for Cardiovascular Secondary Prevention: An Italian Retrospective Observational Analysis of Healthcare Administrative Databases
title_fullStr Coronary Artery Disease in Patients Older than 35 and Eligible for Cardiovascular Secondary Prevention: An Italian Retrospective Observational Analysis of Healthcare Administrative Databases
title_full_unstemmed Coronary Artery Disease in Patients Older than 35 and Eligible for Cardiovascular Secondary Prevention: An Italian Retrospective Observational Analysis of Healthcare Administrative Databases
title_short Coronary Artery Disease in Patients Older than 35 and Eligible for Cardiovascular Secondary Prevention: An Italian Retrospective Observational Analysis of Healthcare Administrative Databases
title_sort coronary artery disease in patients older than 35 and eligible for cardiovascular secondary prevention: an italian retrospective observational analysis of healthcare administrative databases
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540912/
https://www.ncbi.nlm.nih.gov/pubmed/34682831
http://dx.doi.org/10.3390/jcm10204708
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