Cargando…

Osteoblastoma: When the Treatment Is Not Minimally Invasive, an Overview

Background: osteoblastoma is a bone-forming tumor accounting for about 1% of all primary bone tumors and 3% of benign bone tumors. The gold-standard treatment is surgical excision; nevertheless, minimally invasive radiological techniques such as thermoablation and, more recently, high intensity focu...

Descripción completa

Detalles Bibliográficos
Autores principales: Zoccali, Carmine, Novello, Mariangela, Arrigoni, Francesco, Scotto di Uccio, Alessandra, Attala, Dario, Ferraresi, Virginia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540995/
https://www.ncbi.nlm.nih.gov/pubmed/34682768
http://dx.doi.org/10.3390/jcm10204645
_version_ 1784589121884258304
author Zoccali, Carmine
Novello, Mariangela
Arrigoni, Francesco
Scotto di Uccio, Alessandra
Attala, Dario
Ferraresi, Virginia
author_facet Zoccali, Carmine
Novello, Mariangela
Arrigoni, Francesco
Scotto di Uccio, Alessandra
Attala, Dario
Ferraresi, Virginia
author_sort Zoccali, Carmine
collection PubMed
description Background: osteoblastoma is a bone-forming tumor accounting for about 1% of all primary bone tumors and 3% of benign bone tumors. The gold-standard treatment is surgical excision; nevertheless, minimally invasive radiological techniques such as thermoablation and, more recently, high intensity focused ultrasound are gaining more importance. The aim of the present paper is to analyze surgical indications based on our experience and on the evidences in the literature. Methods: all patients affected by osteoblastoma who underwent surgical excision in January 2009 and December 2018 were reviewed; eleven patients were enrolled in the study. The epidemiological aspects, size of the disease and site of onset, symptoms, surgery type, indications, and results are reported for every case. Results: all treatments were based on a preoperative diagnosis; pain was constant in all cases. Intralesional surgeries were performed in 9 out of 11 cases; the remaining 2 cases underwent wide resection. No early or late complications occurred after the surgical procedure. The indications for surgery were lesions very close to nerves or joints, unclear diagnosis, risk of fracture, lesion too large for radiofrequency thermoablation, or failure of minimally invasive treatments. At a medium follow-up of 88 months, no local recurrences were verified. Conclusions: osteoblastoma is a rare tumor with difficult diagnosis. Identification is based on symptoms, imaging, and histology. When possible, minimally invasive techniques is preferred for treatment but surgery is still considered the gold standard.
format Online
Article
Text
id pubmed-8540995
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-85409952021-10-24 Osteoblastoma: When the Treatment Is Not Minimally Invasive, an Overview Zoccali, Carmine Novello, Mariangela Arrigoni, Francesco Scotto di Uccio, Alessandra Attala, Dario Ferraresi, Virginia J Clin Med Article Background: osteoblastoma is a bone-forming tumor accounting for about 1% of all primary bone tumors and 3% of benign bone tumors. The gold-standard treatment is surgical excision; nevertheless, minimally invasive radiological techniques such as thermoablation and, more recently, high intensity focused ultrasound are gaining more importance. The aim of the present paper is to analyze surgical indications based on our experience and on the evidences in the literature. Methods: all patients affected by osteoblastoma who underwent surgical excision in January 2009 and December 2018 were reviewed; eleven patients were enrolled in the study. The epidemiological aspects, size of the disease and site of onset, symptoms, surgery type, indications, and results are reported for every case. Results: all treatments were based on a preoperative diagnosis; pain was constant in all cases. Intralesional surgeries were performed in 9 out of 11 cases; the remaining 2 cases underwent wide resection. No early or late complications occurred after the surgical procedure. The indications for surgery were lesions very close to nerves or joints, unclear diagnosis, risk of fracture, lesion too large for radiofrequency thermoablation, or failure of minimally invasive treatments. At a medium follow-up of 88 months, no local recurrences were verified. Conclusions: osteoblastoma is a rare tumor with difficult diagnosis. Identification is based on symptoms, imaging, and histology. When possible, minimally invasive techniques is preferred for treatment but surgery is still considered the gold standard. MDPI 2021-10-10 /pmc/articles/PMC8540995/ /pubmed/34682768 http://dx.doi.org/10.3390/jcm10204645 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zoccali, Carmine
Novello, Mariangela
Arrigoni, Francesco
Scotto di Uccio, Alessandra
Attala, Dario
Ferraresi, Virginia
Osteoblastoma: When the Treatment Is Not Minimally Invasive, an Overview
title Osteoblastoma: When the Treatment Is Not Minimally Invasive, an Overview
title_full Osteoblastoma: When the Treatment Is Not Minimally Invasive, an Overview
title_fullStr Osteoblastoma: When the Treatment Is Not Minimally Invasive, an Overview
title_full_unstemmed Osteoblastoma: When the Treatment Is Not Minimally Invasive, an Overview
title_short Osteoblastoma: When the Treatment Is Not Minimally Invasive, an Overview
title_sort osteoblastoma: when the treatment is not minimally invasive, an overview
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540995/
https://www.ncbi.nlm.nih.gov/pubmed/34682768
http://dx.doi.org/10.3390/jcm10204645
work_keys_str_mv AT zoccalicarmine osteoblastomawhenthetreatmentisnotminimallyinvasiveanoverview
AT novellomariangela osteoblastomawhenthetreatmentisnotminimallyinvasiveanoverview
AT arrigonifrancesco osteoblastomawhenthetreatmentisnotminimallyinvasiveanoverview
AT scottodiuccioalessandra osteoblastomawhenthetreatmentisnotminimallyinvasiveanoverview
AT attaladario osteoblastomawhenthetreatmentisnotminimallyinvasiveanoverview
AT ferraresivirginia osteoblastomawhenthetreatmentisnotminimallyinvasiveanoverview