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The Epidemiological Patterns of Hepatitis C in Lithuania: Changes in Surveillance from 2005 to 2018

Background and Objectives: Viral hepatitis C infection is an important public health concern worldwide because it is one of the major global causes of death and morbidity. The early identifi-cation of infected people, together with the provision of proper treatment, are the key strategies used in pr...

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Autores principales: Grubyte, Samanta, Urboniene, Jurgita, Nedzinskiene, Laura, Jancoriene, Ligita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541129/
https://www.ncbi.nlm.nih.gov/pubmed/34684157
http://dx.doi.org/10.3390/medicina57101120
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author Grubyte, Samanta
Urboniene, Jurgita
Nedzinskiene, Laura
Jancoriene, Ligita
author_facet Grubyte, Samanta
Urboniene, Jurgita
Nedzinskiene, Laura
Jancoriene, Ligita
author_sort Grubyte, Samanta
collection PubMed
description Background and Objectives: Viral hepatitis C infection is an important public health concern worldwide because it is one of the major global causes of death and morbidity. The early identifi-cation of infected people, together with the provision of proper treatment, are the key strategies used in preventing HCV infection. However, data regarding the epidemiological patterns of hep-atitis C in Lithuania are limited. The aim of this research was to evaluate trends in acute HCV cases registered via the national surveillance system in Lithuania during 2005–2018. Materials and Methods: Incidence rates were calculated for data, stratified by gender, age group (0–24, 25–54, 55–74, and 75+), place of residence (urban or rural), and the Lithuanian county where the case was recorded. The crude incidence rate of hepatitis C was defined as the number of new infec-tions per 100,000 people during a one-year time period. A linear regression was applied to evalu-ate IR trends during the period of 2005–2018. Results: From 2005 to 2018, 572 cases of acute hepa-titis C were registered, and the incidence rate ranged from 2.03 cases per 100,000 people in 2005 to 0.55 in 2016. A statistically significant decreasing trend in the incidence rate was found during the study period (p < 0.0001). Almost 63% of the acute HCV infections recorded via the national surveillance system were in individuals aged from 25 to 54 years. Conclusions: Being male, aged between 25 and 34 years, and living in the city might be important factors for understanding the epidemiological patterns of HCV in Lithuania. Although the number of HCV cases recorded in Lithuania is decreasing, our country has one of the highest IRs compared to other European countries. This shows that a new approach to hepatitis C virus screening strategies is needed.
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spelling pubmed-85411292021-10-24 The Epidemiological Patterns of Hepatitis C in Lithuania: Changes in Surveillance from 2005 to 2018 Grubyte, Samanta Urboniene, Jurgita Nedzinskiene, Laura Jancoriene, Ligita Medicina (Kaunas) Article Background and Objectives: Viral hepatitis C infection is an important public health concern worldwide because it is one of the major global causes of death and morbidity. The early identifi-cation of infected people, together with the provision of proper treatment, are the key strategies used in preventing HCV infection. However, data regarding the epidemiological patterns of hep-atitis C in Lithuania are limited. The aim of this research was to evaluate trends in acute HCV cases registered via the national surveillance system in Lithuania during 2005–2018. Materials and Methods: Incidence rates were calculated for data, stratified by gender, age group (0–24, 25–54, 55–74, and 75+), place of residence (urban or rural), and the Lithuanian county where the case was recorded. The crude incidence rate of hepatitis C was defined as the number of new infec-tions per 100,000 people during a one-year time period. A linear regression was applied to evalu-ate IR trends during the period of 2005–2018. Results: From 2005 to 2018, 572 cases of acute hepa-titis C were registered, and the incidence rate ranged from 2.03 cases per 100,000 people in 2005 to 0.55 in 2016. A statistically significant decreasing trend in the incidence rate was found during the study period (p < 0.0001). Almost 63% of the acute HCV infections recorded via the national surveillance system were in individuals aged from 25 to 54 years. Conclusions: Being male, aged between 25 and 34 years, and living in the city might be important factors for understanding the epidemiological patterns of HCV in Lithuania. Although the number of HCV cases recorded in Lithuania is decreasing, our country has one of the highest IRs compared to other European countries. This shows that a new approach to hepatitis C virus screening strategies is needed. MDPI 2021-10-17 /pmc/articles/PMC8541129/ /pubmed/34684157 http://dx.doi.org/10.3390/medicina57101120 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Grubyte, Samanta
Urboniene, Jurgita
Nedzinskiene, Laura
Jancoriene, Ligita
The Epidemiological Patterns of Hepatitis C in Lithuania: Changes in Surveillance from 2005 to 2018
title The Epidemiological Patterns of Hepatitis C in Lithuania: Changes in Surveillance from 2005 to 2018
title_full The Epidemiological Patterns of Hepatitis C in Lithuania: Changes in Surveillance from 2005 to 2018
title_fullStr The Epidemiological Patterns of Hepatitis C in Lithuania: Changes in Surveillance from 2005 to 2018
title_full_unstemmed The Epidemiological Patterns of Hepatitis C in Lithuania: Changes in Surveillance from 2005 to 2018
title_short The Epidemiological Patterns of Hepatitis C in Lithuania: Changes in Surveillance from 2005 to 2018
title_sort epidemiological patterns of hepatitis c in lithuania: changes in surveillance from 2005 to 2018
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541129/
https://www.ncbi.nlm.nih.gov/pubmed/34684157
http://dx.doi.org/10.3390/medicina57101120
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