PIM1 Inhibition Affects Glioblastoma Stem Cell Behavior and Kills Glioblastoma Stem-like Cells

Despite comprehensive therapy and extensive research, glioblastoma (GBM) still represents the most aggressive brain tumor in adults. Glioma stem cells (GSCs) are thought to play a major role in tumor progression and resistance of GBM cells to radiochemotherapy. The PIM1 kinase has become a focus in...

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Detalles Bibliográficos
Autores principales: Seifert, Carolin, Balz, Ellen, Herzog, Susann, Korolev, Anna, Gaßmann, Sebastian, Paland, Heiko, Fink, Matthias A., Grube, Markus, Marx, Sascha, Jedlitschky, Gabriele, Tzvetkov, Mladen V., Rauch, Bernhard H., Schroeder, Henry W. S., Bien-Möller, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541331/
https://www.ncbi.nlm.nih.gov/pubmed/34681783
http://dx.doi.org/10.3390/ijms222011126

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