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Minimizing Oxidation of Freeze-Dried Monoclonal Antibodies in Polymeric Vials Using a Smart Packaging Approach

Primary containers made of cyclic olefin polymer (COP) have recently gained attention since they may overcome several risks and shortcomings of glass containers as they exhibit a high break resistance, biocompatibility, and homogeneous heat transfer during lyophilization. On the downside, COP is mor...

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Detalles Bibliográficos
Autores principales: Härdter, Nicole, Menzen, Tim, Winter, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541347/
https://www.ncbi.nlm.nih.gov/pubmed/34683987
http://dx.doi.org/10.3390/pharmaceutics13101695