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Potential for Interspecies Toxicity Estimation in Soil Invertebrates

Interspecies correlation estimation (ICE) models are linear regressions that predict toxicity to a species with few data using a known toxicity value in a surrogate species. ICE models are well established for estimating toxicity to fish and aquatic invertebrates but have not been generally develope...

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Autores principales: Barron, Mace G., Lambert, Faith N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541476/
https://www.ncbi.nlm.nih.gov/pubmed/34678961
http://dx.doi.org/10.3390/toxics9100265
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author Barron, Mace G.
Lambert, Faith N.
author_facet Barron, Mace G.
Lambert, Faith N.
author_sort Barron, Mace G.
collection PubMed
description Interspecies correlation estimation (ICE) models are linear regressions that predict toxicity to a species with few data using a known toxicity value in a surrogate species. ICE models are well established for estimating toxicity to fish and aquatic invertebrates but have not been generally developed or applied to soil organisms. To facilitate the development of ICE models for soil invertebrates, a database of single chemical toxicity values was compiled from knowledgebases and reports that included 853 records encompassing 192 chemicals and 12 species. Most toxicity data for single chemicals tested in soil media were for species of earthworms, with only limited data for other species and taxa. ICE models were developed for eleven separate species pairs as least squares log-linear regressions of acute toxicity values of the same chemicals tested in both the surrogate and predicted species of soil organisms. Model uncertainty was assessed using leave one out cross-validation as the fold difference between a predicted and measured toxicity value. ICE models showed high accuracy within order (e.g., earthworm to earthworm), but less prediction accuracy in the two across-taxa models (Arthropoda to Annelida and the inverse). This study provides a proof-of-concept demonstration that ICE models can be developed for soil invertebrates.
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spelling pubmed-85414762021-10-24 Potential for Interspecies Toxicity Estimation in Soil Invertebrates Barron, Mace G. Lambert, Faith N. Toxics Article Interspecies correlation estimation (ICE) models are linear regressions that predict toxicity to a species with few data using a known toxicity value in a surrogate species. ICE models are well established for estimating toxicity to fish and aquatic invertebrates but have not been generally developed or applied to soil organisms. To facilitate the development of ICE models for soil invertebrates, a database of single chemical toxicity values was compiled from knowledgebases and reports that included 853 records encompassing 192 chemicals and 12 species. Most toxicity data for single chemicals tested in soil media were for species of earthworms, with only limited data for other species and taxa. ICE models were developed for eleven separate species pairs as least squares log-linear regressions of acute toxicity values of the same chemicals tested in both the surrogate and predicted species of soil organisms. Model uncertainty was assessed using leave one out cross-validation as the fold difference between a predicted and measured toxicity value. ICE models showed high accuracy within order (e.g., earthworm to earthworm), but less prediction accuracy in the two across-taxa models (Arthropoda to Annelida and the inverse). This study provides a proof-of-concept demonstration that ICE models can be developed for soil invertebrates. MDPI 2021-10-14 /pmc/articles/PMC8541476/ /pubmed/34678961 http://dx.doi.org/10.3390/toxics9100265 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Barron, Mace G.
Lambert, Faith N.
Potential for Interspecies Toxicity Estimation in Soil Invertebrates
title Potential for Interspecies Toxicity Estimation in Soil Invertebrates
title_full Potential for Interspecies Toxicity Estimation in Soil Invertebrates
title_fullStr Potential for Interspecies Toxicity Estimation in Soil Invertebrates
title_full_unstemmed Potential for Interspecies Toxicity Estimation in Soil Invertebrates
title_short Potential for Interspecies Toxicity Estimation in Soil Invertebrates
title_sort potential for interspecies toxicity estimation in soil invertebrates
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541476/
https://www.ncbi.nlm.nih.gov/pubmed/34678961
http://dx.doi.org/10.3390/toxics9100265
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