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Marine Polysaccharides for Wound Dressings Application: An Overview

Wound dressings have become a crucial treatment for wound healing due to their convenience, low cost, and prolonged wound management. As cutting-edge biomaterials, marine polysaccharides are divided from most marine organisms. It possesses various bioactivities, which allowing them to be processed i...

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Autores principales: Shen, Shenghai, Chen, Xiaowen, Shen, Zhewen, Chen, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541487/
https://www.ncbi.nlm.nih.gov/pubmed/34683959
http://dx.doi.org/10.3390/pharmaceutics13101666
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author Shen, Shenghai
Chen, Xiaowen
Shen, Zhewen
Chen, Hao
author_facet Shen, Shenghai
Chen, Xiaowen
Shen, Zhewen
Chen, Hao
author_sort Shen, Shenghai
collection PubMed
description Wound dressings have become a crucial treatment for wound healing due to their convenience, low cost, and prolonged wound management. As cutting-edge biomaterials, marine polysaccharides are divided from most marine organisms. It possesses various bioactivities, which allowing them to be processed into various forms of wound dressings. Therefore, a comprehensive understanding of the application of marine polysaccharides in wound dressings is particularly important for the studies of wound therapy. In this review, we first introduce the wound healing process and describe the characteristics of modern commonly used dressings. Then, the properties of various marine polysaccharides and their application in wound dressing development are outlined. Finally, strategies for developing and enhancing marine polysaccharide wound dressings are described, and an outlook of these dressings is given. The diverse bioactivities of marine polysaccharides including antibacterial, anti-inflammatory, haemostatic properties, etc., providing excellent wound management and accelerate wound healing. Meanwhile, these biomaterials have higher biocompatibility and biodegradability compared to synthetic ones. On the other hand, marine polysaccharides can be combined with copolymers and active substances to prepare various forms of dressings. Among them, emerging types of dressings such as nanofibers, smart hydrogels and injectable hydrogels are at the research frontier of their development. Therefore, marine polysaccharides are essential materials in wound dressings fabrication and have a promising future.
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spelling pubmed-85414872021-10-24 Marine Polysaccharides for Wound Dressings Application: An Overview Shen, Shenghai Chen, Xiaowen Shen, Zhewen Chen, Hao Pharmaceutics Review Wound dressings have become a crucial treatment for wound healing due to their convenience, low cost, and prolonged wound management. As cutting-edge biomaterials, marine polysaccharides are divided from most marine organisms. It possesses various bioactivities, which allowing them to be processed into various forms of wound dressings. Therefore, a comprehensive understanding of the application of marine polysaccharides in wound dressings is particularly important for the studies of wound therapy. In this review, we first introduce the wound healing process and describe the characteristics of modern commonly used dressings. Then, the properties of various marine polysaccharides and their application in wound dressing development are outlined. Finally, strategies for developing and enhancing marine polysaccharide wound dressings are described, and an outlook of these dressings is given. The diverse bioactivities of marine polysaccharides including antibacterial, anti-inflammatory, haemostatic properties, etc., providing excellent wound management and accelerate wound healing. Meanwhile, these biomaterials have higher biocompatibility and biodegradability compared to synthetic ones. On the other hand, marine polysaccharides can be combined with copolymers and active substances to prepare various forms of dressings. Among them, emerging types of dressings such as nanofibers, smart hydrogels and injectable hydrogels are at the research frontier of their development. Therefore, marine polysaccharides are essential materials in wound dressings fabrication and have a promising future. MDPI 2021-10-12 /pmc/articles/PMC8541487/ /pubmed/34683959 http://dx.doi.org/10.3390/pharmaceutics13101666 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Shen, Shenghai
Chen, Xiaowen
Shen, Zhewen
Chen, Hao
Marine Polysaccharides for Wound Dressings Application: An Overview
title Marine Polysaccharides for Wound Dressings Application: An Overview
title_full Marine Polysaccharides for Wound Dressings Application: An Overview
title_fullStr Marine Polysaccharides for Wound Dressings Application: An Overview
title_full_unstemmed Marine Polysaccharides for Wound Dressings Application: An Overview
title_short Marine Polysaccharides for Wound Dressings Application: An Overview
title_sort marine polysaccharides for wound dressings application: an overview
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541487/
https://www.ncbi.nlm.nih.gov/pubmed/34683959
http://dx.doi.org/10.3390/pharmaceutics13101666
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