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Acute and Chronic Effects of COVID-19 on the Cardiovascular System

COVID-19 has shown significant morbidity with the involvement of multiple systems, including the cardiovascular system. Cardiovascular manifestations in the acute phase can include myocardial injury itself, myocardial infarction, venous thromboembolic events, myocarditis, Takotsubo syndrome, and dif...

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Autores principales: Arévalos, Victor, Ortega-Paz, Luis, Rodríguez-Arias, Juan José, Calvo López, Margarita, Castrillo-Golvano, Leticia, Salazar-Rodríguez, Anthony, Sabaté-Tormos, Marta, Spione, Francesco, Sabaté, Manel, Brugaletta, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541609/
https://www.ncbi.nlm.nih.gov/pubmed/34677197
http://dx.doi.org/10.3390/jcdd8100128
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author Arévalos, Victor
Ortega-Paz, Luis
Rodríguez-Arias, Juan José
Calvo López, Margarita
Castrillo-Golvano, Leticia
Salazar-Rodríguez, Anthony
Sabaté-Tormos, Marta
Spione, Francesco
Sabaté, Manel
Brugaletta, Salvatore
author_facet Arévalos, Victor
Ortega-Paz, Luis
Rodríguez-Arias, Juan José
Calvo López, Margarita
Castrillo-Golvano, Leticia
Salazar-Rodríguez, Anthony
Sabaté-Tormos, Marta
Spione, Francesco
Sabaté, Manel
Brugaletta, Salvatore
author_sort Arévalos, Victor
collection PubMed
description COVID-19 has shown significant morbidity with the involvement of multiple systems, including the cardiovascular system. Cardiovascular manifestations in the acute phase can include myocardial injury itself, myocardial infarction, venous thromboembolic events, myocarditis, Takotsubo syndrome, and different arrhythmic events. Myocardial injury defined by the rise of cardiac biomarkers in blood has been found in multiple studies with a prevalence of about 20%. Its presence is related to worse clinical outcomes and in-hospital mortality. The mechanisms of myocardial injury have been the subject of intense research but still need to be clarified. The characterization of the cardiac affectation with echocardiography and cardiac magnetic resonance has found mixed results in different studies, with a striking incidence of imaging criteria for myocarditis. Regarding post-acute and chronic follow-up results, the persistence of symptoms and imaging changes in recovered COVID-19 patients has raised concerns about the duration and the possible significance of these findings. Even though the knowledge about this disease has increased incredibly in the last year, many aspects are still unclear and warrant further research.
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spelling pubmed-85416092021-10-24 Acute and Chronic Effects of COVID-19 on the Cardiovascular System Arévalos, Victor Ortega-Paz, Luis Rodríguez-Arias, Juan José Calvo López, Margarita Castrillo-Golvano, Leticia Salazar-Rodríguez, Anthony Sabaté-Tormos, Marta Spione, Francesco Sabaté, Manel Brugaletta, Salvatore J Cardiovasc Dev Dis Review COVID-19 has shown significant morbidity with the involvement of multiple systems, including the cardiovascular system. Cardiovascular manifestations in the acute phase can include myocardial injury itself, myocardial infarction, venous thromboembolic events, myocarditis, Takotsubo syndrome, and different arrhythmic events. Myocardial injury defined by the rise of cardiac biomarkers in blood has been found in multiple studies with a prevalence of about 20%. Its presence is related to worse clinical outcomes and in-hospital mortality. The mechanisms of myocardial injury have been the subject of intense research but still need to be clarified. The characterization of the cardiac affectation with echocardiography and cardiac magnetic resonance has found mixed results in different studies, with a striking incidence of imaging criteria for myocarditis. Regarding post-acute and chronic follow-up results, the persistence of symptoms and imaging changes in recovered COVID-19 patients has raised concerns about the duration and the possible significance of these findings. Even though the knowledge about this disease has increased incredibly in the last year, many aspects are still unclear and warrant further research. MDPI 2021-10-05 /pmc/articles/PMC8541609/ /pubmed/34677197 http://dx.doi.org/10.3390/jcdd8100128 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Arévalos, Victor
Ortega-Paz, Luis
Rodríguez-Arias, Juan José
Calvo López, Margarita
Castrillo-Golvano, Leticia
Salazar-Rodríguez, Anthony
Sabaté-Tormos, Marta
Spione, Francesco
Sabaté, Manel
Brugaletta, Salvatore
Acute and Chronic Effects of COVID-19 on the Cardiovascular System
title Acute and Chronic Effects of COVID-19 on the Cardiovascular System
title_full Acute and Chronic Effects of COVID-19 on the Cardiovascular System
title_fullStr Acute and Chronic Effects of COVID-19 on the Cardiovascular System
title_full_unstemmed Acute and Chronic Effects of COVID-19 on the Cardiovascular System
title_short Acute and Chronic Effects of COVID-19 on the Cardiovascular System
title_sort acute and chronic effects of covid-19 on the cardiovascular system
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541609/
https://www.ncbi.nlm.nih.gov/pubmed/34677197
http://dx.doi.org/10.3390/jcdd8100128
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