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Gastrointestinal Bleeding in Patients with SARS-CoV-2 Infection Managed by Interventional Radiology

Background: This study was conducted to evaluate the technical and clinical success of trans-arterial embolization (TAE) as a treatment of gastrointestinal bleeding (GIB) in Coronavirus Disease 2019 (COVID-19) patients and to describe its safety; moreover, we describe the characteristics of these pa...

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Autores principales: Ierardi, Anna Maria, Coppola, Andrea, Tortora, Silvia, Valconi, Elena, Piacentino, Filippo, Fontana, Federico, Stellato, Elvira, Cogliati, Chiara Beatrice, Torzillo, Daniela, Giampalma, Emanuela, Renzulli, Matteo, Bargellini, Irene, Cioni, Roberto, Scandiffio, Rossella, Spinazzola, Angelo, Foà, Riccardo Alessandro, Del Giudice, Costantino, Venturini, Massimo, Carrafiello, Gianpaolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541615/
https://www.ncbi.nlm.nih.gov/pubmed/34682879
http://dx.doi.org/10.3390/jcm10204758
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author Ierardi, Anna Maria
Coppola, Andrea
Tortora, Silvia
Valconi, Elena
Piacentino, Filippo
Fontana, Federico
Stellato, Elvira
Cogliati, Chiara Beatrice
Torzillo, Daniela
Giampalma, Emanuela
Renzulli, Matteo
Bargellini, Irene
Cioni, Roberto
Scandiffio, Rossella
Spinazzola, Angelo
Foà, Riccardo Alessandro
Del Giudice, Costantino
Venturini, Massimo
Carrafiello, Gianpaolo
author_facet Ierardi, Anna Maria
Coppola, Andrea
Tortora, Silvia
Valconi, Elena
Piacentino, Filippo
Fontana, Federico
Stellato, Elvira
Cogliati, Chiara Beatrice
Torzillo, Daniela
Giampalma, Emanuela
Renzulli, Matteo
Bargellini, Irene
Cioni, Roberto
Scandiffio, Rossella
Spinazzola, Angelo
Foà, Riccardo Alessandro
Del Giudice, Costantino
Venturini, Massimo
Carrafiello, Gianpaolo
author_sort Ierardi, Anna Maria
collection PubMed
description Background: This study was conducted to evaluate the technical and clinical success of trans-arterial embolization (TAE) as a treatment of gastrointestinal bleeding (GIB) in Coronavirus Disease 2019 (COVID-19) patients and to describe its safety; moreover, we describe the characteristics of these patients. Methods: Thirty-four COVID-19 hospitalized patients presented with GIB. Risk factors, drugs administered for COVID-19 infection, and clinical and biological parameters were evaluated. Furthermore, intraprocedural data and outcomes of embolization were analyzed. Results: GIB was more frequent in male. Overweight, hypertension, diabetes, previous cardiac disease, and anticoagulation preadmission (48.5%) were frequently found in our population. Previous or actual COVID Acute respiratory distress syndrome (ARDS) and a high level of D-dimer were encountered in most cases. Upper GIB was more frequent than lower GIB. Technical and clinical success rates of embolization were 88.2% and 94.1%, respectively. The complication rate was 5.9%. Conclusions: Our study highlights the most frequent characteristics of COVID-19 patients with GIB. Embolization is feasible, effective, and safe.
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spelling pubmed-85416152021-10-24 Gastrointestinal Bleeding in Patients with SARS-CoV-2 Infection Managed by Interventional Radiology Ierardi, Anna Maria Coppola, Andrea Tortora, Silvia Valconi, Elena Piacentino, Filippo Fontana, Federico Stellato, Elvira Cogliati, Chiara Beatrice Torzillo, Daniela Giampalma, Emanuela Renzulli, Matteo Bargellini, Irene Cioni, Roberto Scandiffio, Rossella Spinazzola, Angelo Foà, Riccardo Alessandro Del Giudice, Costantino Venturini, Massimo Carrafiello, Gianpaolo J Clin Med Article Background: This study was conducted to evaluate the technical and clinical success of trans-arterial embolization (TAE) as a treatment of gastrointestinal bleeding (GIB) in Coronavirus Disease 2019 (COVID-19) patients and to describe its safety; moreover, we describe the characteristics of these patients. Methods: Thirty-four COVID-19 hospitalized patients presented with GIB. Risk factors, drugs administered for COVID-19 infection, and clinical and biological parameters were evaluated. Furthermore, intraprocedural data and outcomes of embolization were analyzed. Results: GIB was more frequent in male. Overweight, hypertension, diabetes, previous cardiac disease, and anticoagulation preadmission (48.5%) were frequently found in our population. Previous or actual COVID Acute respiratory distress syndrome (ARDS) and a high level of D-dimer were encountered in most cases. Upper GIB was more frequent than lower GIB. Technical and clinical success rates of embolization were 88.2% and 94.1%, respectively. The complication rate was 5.9%. Conclusions: Our study highlights the most frequent characteristics of COVID-19 patients with GIB. Embolization is feasible, effective, and safe. MDPI 2021-10-17 /pmc/articles/PMC8541615/ /pubmed/34682879 http://dx.doi.org/10.3390/jcm10204758 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ierardi, Anna Maria
Coppola, Andrea
Tortora, Silvia
Valconi, Elena
Piacentino, Filippo
Fontana, Federico
Stellato, Elvira
Cogliati, Chiara Beatrice
Torzillo, Daniela
Giampalma, Emanuela
Renzulli, Matteo
Bargellini, Irene
Cioni, Roberto
Scandiffio, Rossella
Spinazzola, Angelo
Foà, Riccardo Alessandro
Del Giudice, Costantino
Venturini, Massimo
Carrafiello, Gianpaolo
Gastrointestinal Bleeding in Patients with SARS-CoV-2 Infection Managed by Interventional Radiology
title Gastrointestinal Bleeding in Patients with SARS-CoV-2 Infection Managed by Interventional Radiology
title_full Gastrointestinal Bleeding in Patients with SARS-CoV-2 Infection Managed by Interventional Radiology
title_fullStr Gastrointestinal Bleeding in Patients with SARS-CoV-2 Infection Managed by Interventional Radiology
title_full_unstemmed Gastrointestinal Bleeding in Patients with SARS-CoV-2 Infection Managed by Interventional Radiology
title_short Gastrointestinal Bleeding in Patients with SARS-CoV-2 Infection Managed by Interventional Radiology
title_sort gastrointestinal bleeding in patients with sars-cov-2 infection managed by interventional radiology
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541615/
https://www.ncbi.nlm.nih.gov/pubmed/34682879
http://dx.doi.org/10.3390/jcm10204758
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