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Physiological and Pathological Roles of Aldose Reductase

Aldose reductase (AR) is an aldo-keto reductase that catalyzes the first step in the polyol pathway which converts glucose to sorbitol. Under normal glucose homeostasis the pathway represents a minor route of glucose metabolism that operates in parallel with glycolysis. However, during hyperglycemia...

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Detalles Bibliográficos
Autores principales: Singh, Mahavir, Kapoor, Aniruddh, Bhatnagar, Aruni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541668/
https://www.ncbi.nlm.nih.gov/pubmed/34677370
http://dx.doi.org/10.3390/metabo11100655

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