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Functional Depletion of HSP72 by siRNA and Quercetin Enhances Vorinostat-Induced Apoptosis in an HSP72-Overexpressing Cutaneous T-Cell Lymphoma Cell Line, Hut78

Histone deacetylase inhibitors (HDACis) are one of the therapeutic options for cutaneous T-cell lymphoma (CTCL), but they have limited effects. We previously demonstrated that HSP72 overexpression is associated with chemoresistance to HDACis in lymphoma cells. The purpose of this study was to invest...

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Detalles Bibliográficos
Autores principales: Fujii, Kazuyasu, Idogawa, Masashi, Suzuki, Norihiro, Iwatsuki, Keiji, Kanekura, Takuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541672/
https://www.ncbi.nlm.nih.gov/pubmed/34681913
http://dx.doi.org/10.3390/ijms222011258

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