Primary Combined Hepatocellular-Cholangiocarcinoma: A Case of Underdiagnosed Primary Liver Cancer

Combined hepatocellular-cholangiocarcinoma (CHC) is a rare primary tumor of the liver. Histologically, it comprises components of both hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) but is associated with a worse prognosis. International guidelines regarding its management are scarce, wi...

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Autores principales: Ayas, Mohamad F, Affas, Saif, Ayas, Zayd, Chand, Momal, Hadid, Tarik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Gastroenterology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541753/
https://www.ncbi.nlm.nih.gov/pubmed/34703709
http://dx.doi.org/10.7759/cureus.18224
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author Ayas, Mohamad F
Affas, Saif
Ayas, Zayd
Chand, Momal
Hadid, Tarik
author_facet Ayas, Mohamad F
Affas, Saif
Ayas, Zayd
Chand, Momal
Hadid, Tarik
author_sort Ayas, Mohamad F
collection PubMed
description Combined hepatocellular-cholangiocarcinoma (CHC) is a rare primary tumor of the liver. Histologically, it comprises components of both hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) but is associated with a worse prognosis. International guidelines regarding its management are scarce, with surgical management (major hepatectomy) being the treatment of choice. In this report, we present a challenging case of a 73-year-old male with primary CHC who was not a surgical candidate but underwent hepatic artery radioembolization instead.
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spelling pubmed-85417532021-10-25 Primary Combined Hepatocellular-Cholangiocarcinoma: A Case of Underdiagnosed Primary Liver Cancer Ayas, Mohamad F Affas, Saif Ayas, Zayd Chand, Momal Hadid, Tarik Cureus Gastroenterology Combined hepatocellular-cholangiocarcinoma (CHC) is a rare primary tumor of the liver. Histologically, it comprises components of both hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) but is associated with a worse prognosis. International guidelines regarding its management are scarce, with surgical management (major hepatectomy) being the treatment of choice. In this report, we present a challenging case of a 73-year-old male with primary CHC who was not a surgical candidate but underwent hepatic artery radioembolization instead. Cureus 2021-09-23 /pmc/articles/PMC8541753/ /pubmed/34703709 http://dx.doi.org/10.7759/cureus.18224 Text en Copyright © 2021, Ayas et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Gastroenterology
Ayas, Mohamad F
Affas, Saif
Ayas, Zayd
Chand, Momal
Hadid, Tarik
Primary Combined Hepatocellular-Cholangiocarcinoma: A Case of Underdiagnosed Primary Liver Cancer
title Primary Combined Hepatocellular-Cholangiocarcinoma: A Case of Underdiagnosed Primary Liver Cancer
title_full Primary Combined Hepatocellular-Cholangiocarcinoma: A Case of Underdiagnosed Primary Liver Cancer
title_fullStr Primary Combined Hepatocellular-Cholangiocarcinoma: A Case of Underdiagnosed Primary Liver Cancer
title_full_unstemmed Primary Combined Hepatocellular-Cholangiocarcinoma: A Case of Underdiagnosed Primary Liver Cancer
title_short Primary Combined Hepatocellular-Cholangiocarcinoma: A Case of Underdiagnosed Primary Liver Cancer
title_sort primary combined hepatocellular-cholangiocarcinoma: a case of underdiagnosed primary liver cancer
topic Gastroenterology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541753/
https://www.ncbi.nlm.nih.gov/pubmed/34703709
http://dx.doi.org/10.7759/cureus.18224
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