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MDM4 Isoform Expression in Melanoma Supports an Oncogenic Role for MDM4-A
The p53 tumor suppressor integrates upstream signals such as DNA damage and active oncogenes to initiate cell cycle arrest or apoptosis. This response is critical to halting inappropriate growth signals. As such, p53 activity is lost in cancer. In melanoma, however, the p53 gene is intact in a repor...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541850/ https://www.ncbi.nlm.nih.gov/pubmed/34697572 http://dx.doi.org/10.1155/2021/3087579 |