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A Novel Developed Bioactive Composite Resin Containing Silver/Zinc Oxide (Ag/ZnO) Nanoparticles as an Antimicrobial Material against Streptococcus mutans, Lactobacillus, and Candida albicans

AIM: The objectives of this study were to develop a new bioactive composite resin containing silver/zinc oxide (Ag/ZnO) nanoparticles and investigate the effects on mechanical, cytotoxic, biocompatibility, and antimicrobial properties. MATERIALS AND METHODS: Disc-shaped specimens were prepared from...

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Autores principales: Kachoei, Mojgan, Divband, Baharak, Rahbar, Mahdi, Esmaeilzadeh, Mahdiyeh, Ghanizadeh, Milad, Alam, Mostafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541865/
https://www.ncbi.nlm.nih.gov/pubmed/34697547
http://dx.doi.org/10.1155/2021/4743411
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author Kachoei, Mojgan
Divband, Baharak
Rahbar, Mahdi
Esmaeilzadeh, Mahdiyeh
Ghanizadeh, Milad
Alam, Mostafa
author_facet Kachoei, Mojgan
Divband, Baharak
Rahbar, Mahdi
Esmaeilzadeh, Mahdiyeh
Ghanizadeh, Milad
Alam, Mostafa
author_sort Kachoei, Mojgan
collection PubMed
description AIM: The objectives of this study were to develop a new bioactive composite resin containing silver/zinc oxide (Ag/ZnO) nanoparticles and investigate the effects on mechanical, cytotoxic, biocompatibility, and antimicrobial properties. MATERIALS AND METHODS: Disc-shaped specimens were prepared from composite with and without nanoparticles in separate culture media containing Streptococcus mutans, Lactobacillus, and Candida albicans. Bracket bonding evaluation was performed on composite without nanoparticles (O), composite containing ZnO (Z) nanoparticles, composite containing ZnO nanoparticles and silver ions (A&Z), and composite containing Ag/ZnO nanoparticles (AZ) synthesized using optical precipitation. RESULTS: Composite resin with nanoparticles (AZ, A&Z, and Z) showed significant antimicrobial properties (P < 0.05). The mean shear bond strength of A&Z composite resin (13.61 ± 0.73 MPa) was significantly less than that of conventional composite resin (19.03 ± 4.12 MPa) (P < 0.05). In addition, the mean shear bond strength of AZ composite resin (20.49 ± 1.03 MPa) was significantly higher than that of Z (16.35 ± 1.03 MPa) and A&Z composite resins. CONCLUSIONS: Incorporation of ZnO nanoparticles and their compounds into orthodontic composite resins induced antibacterial properties against oral pathogens, and of all these nanoparticles, the AZ group exhibited the best antimicrobial activity and highest shear bond strength.
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spelling pubmed-85418652021-10-24 A Novel Developed Bioactive Composite Resin Containing Silver/Zinc Oxide (Ag/ZnO) Nanoparticles as an Antimicrobial Material against Streptococcus mutans, Lactobacillus, and Candida albicans Kachoei, Mojgan Divband, Baharak Rahbar, Mahdi Esmaeilzadeh, Mahdiyeh Ghanizadeh, Milad Alam, Mostafa Evid Based Complement Alternat Med Research Article AIM: The objectives of this study were to develop a new bioactive composite resin containing silver/zinc oxide (Ag/ZnO) nanoparticles and investigate the effects on mechanical, cytotoxic, biocompatibility, and antimicrobial properties. MATERIALS AND METHODS: Disc-shaped specimens were prepared from composite with and without nanoparticles in separate culture media containing Streptococcus mutans, Lactobacillus, and Candida albicans. Bracket bonding evaluation was performed on composite without nanoparticles (O), composite containing ZnO (Z) nanoparticles, composite containing ZnO nanoparticles and silver ions (A&Z), and composite containing Ag/ZnO nanoparticles (AZ) synthesized using optical precipitation. RESULTS: Composite resin with nanoparticles (AZ, A&Z, and Z) showed significant antimicrobial properties (P < 0.05). The mean shear bond strength of A&Z composite resin (13.61 ± 0.73 MPa) was significantly less than that of conventional composite resin (19.03 ± 4.12 MPa) (P < 0.05). In addition, the mean shear bond strength of AZ composite resin (20.49 ± 1.03 MPa) was significantly higher than that of Z (16.35 ± 1.03 MPa) and A&Z composite resins. CONCLUSIONS: Incorporation of ZnO nanoparticles and their compounds into orthodontic composite resins induced antibacterial properties against oral pathogens, and of all these nanoparticles, the AZ group exhibited the best antimicrobial activity and highest shear bond strength. Hindawi 2021-10-16 /pmc/articles/PMC8541865/ /pubmed/34697547 http://dx.doi.org/10.1155/2021/4743411 Text en Copyright © 2021 Mojgan Kachoei et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Kachoei, Mojgan
Divband, Baharak
Rahbar, Mahdi
Esmaeilzadeh, Mahdiyeh
Ghanizadeh, Milad
Alam, Mostafa
A Novel Developed Bioactive Composite Resin Containing Silver/Zinc Oxide (Ag/ZnO) Nanoparticles as an Antimicrobial Material against Streptococcus mutans, Lactobacillus, and Candida albicans
title A Novel Developed Bioactive Composite Resin Containing Silver/Zinc Oxide (Ag/ZnO) Nanoparticles as an Antimicrobial Material against Streptococcus mutans, Lactobacillus, and Candida albicans
title_full A Novel Developed Bioactive Composite Resin Containing Silver/Zinc Oxide (Ag/ZnO) Nanoparticles as an Antimicrobial Material against Streptococcus mutans, Lactobacillus, and Candida albicans
title_fullStr A Novel Developed Bioactive Composite Resin Containing Silver/Zinc Oxide (Ag/ZnO) Nanoparticles as an Antimicrobial Material against Streptococcus mutans, Lactobacillus, and Candida albicans
title_full_unstemmed A Novel Developed Bioactive Composite Resin Containing Silver/Zinc Oxide (Ag/ZnO) Nanoparticles as an Antimicrobial Material against Streptococcus mutans, Lactobacillus, and Candida albicans
title_short A Novel Developed Bioactive Composite Resin Containing Silver/Zinc Oxide (Ag/ZnO) Nanoparticles as an Antimicrobial Material against Streptococcus mutans, Lactobacillus, and Candida albicans
title_sort novel developed bioactive composite resin containing silver/zinc oxide (ag/zno) nanoparticles as an antimicrobial material against streptococcus mutans, lactobacillus, and candida albicans
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541865/
https://www.ncbi.nlm.nih.gov/pubmed/34697547
http://dx.doi.org/10.1155/2021/4743411
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