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The IL-6R and Bmi-1 axis controls self-renewal and chemoresistance of head and neck cancer stem cells

Despite major progress in elucidating the pathobiology of head and neck squamous cell carcinoma (HNSCC), the high frequency of disease relapse correlates with unacceptably deficient patient survival. We previously showed that cancer stem-like cells (CSCs) drive tumorigenesis and progression of HNSCC...

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Detalles Bibliográficos
Autores principales:	Herzog, Alexandra E., Warner, Kristy A., Zhang, Zhaocheng, Bellile, Emily, Bhagat, Meera A., Castilho, Rogerio M., Wolf, Gregory T., Polverini, Peter J., Pearson, Alexander T., Nör, Jacques E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542035/ https://www.ncbi.nlm.nih.gov/pubmed/34689150 http://dx.doi.org/10.1038/s41419-021-04268-5

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